Managing chemotherapy extravasation in totally implantable central venous access: Use of subcutaneous wash-out technique.

CONCLUSION: This study would argue for the feasibility and effectiveness of subcutaneous wash-out in the treatment of chemotherapy extravasations. PMID: 32056485 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research

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Many pediatric patients undergo placement of tunneled central venous catheters (TCVCs) to facilitate critical treatment, such as chemotherapy, parental nutrition, and antibiotics. Both infectious- and mechanical-related complication can lead to premature catheter removal, resulting in increased healthcare cost and treatment delay. We attempted to identify preoperative factors correlating with an increased risk of central-line-associated bloodstream infection (CLABSI) and early catheter removal.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Pediatric surgery Source Type: research
Central venous catheterisation is a technically challenging procedure with numerous indications, including fluid resuscitation, total parenteral nutrition, chemotherapy or central venous pressure monitoring. There has been recent debate regarding the optimal technique for guidewire placement; a thin-walled introducer needle (TWN) or a catheter-over-needle (CON) technique, with the latter being suggested by the American Society of Anaesthesiologists as providing more stable access if manometry is used for venous confirmation [1].
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research
Labianca In the general population, the incidence of thromboembolic events is 117 cases/100,000 inhabitants/year, while in cancer patient incidence, it is four-fold higher, especially in patients who receive chemotherapy and who are affected by pancreatic, lung or gastric cancer. At the basis of venous thromboembolism (VTE) there is the so-called Virchow triad, but tumor cells can activate coagulation pathway by various direct and indirect mechanisms, and chemotherapy can contribute to VTE onset. For these reasons, several studies were conducted in order to assess efficacy and safety of the use of anticoagulant therap...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Conclusion: Our study will provide evidence for the effects of PICC versus CVC for venous access. Ethics and dissemination: This SR has obtained formal ethical approval and was prospectively registered in Open Science Framework. The findings of this SR will be disseminated through peer-reviewed publications or conference presentations. Registration: osf.io/xvhzf. Ethical approval: 69003717.2.0000.5505.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Abstract Breast cancer management is a rapidly evolving field. Diagnosis and treatment options have changed dramatically over the years, as have options for vascular access devices used to administer therapies. We now need to critically rethink vascular access device options for our breast cancer patients. Breast cancer (BC) is the most commonly diagnosed cancer among Canadian women. Although BC incidence continues to rise, the overall mortality rate in Canada is the lowest it has been for 70 years. The five-year net survival is 87%, and 83% of women are alive at 10 years. New oral therapies, shorter dose-dense tr...
Source: British Journal of Nursing - Category: Nursing Authors: Tags: Br J Nurs Source Type: research
AbstractBackgroundCatheter-related bloodstream infections (CRBSIs) increase morbidity and mortality, prolong hospitalization and generate considerable medical costs. Recent guidelines for CRBSI recommend empirical therapy against Gram-positive bacteria (GPB) and restrict coverage for Gram-negative bacteria (GNB) only to specific circumstances.ObjectivesTo investigate predictors of GNB aetiology in CRBSI and to assess the predictors of outcome in patients with CRBSI.MethodsPatients with CRBSI were selected from the PROBAC cohort, a prospective, observational, multicentre national cohort study including patients with bloodst...
Source: Journal of Antimicrobial Chemotherapy - Category: Microbiology Source Type: research
We reported an unusual case of a breast cancer patient with a persistent left superior vena cava detected after a peripherally inserted central catheter insertion. The patient had undergone a modified radical mastectomy and needed to insert a peripherally inserted central catheter for chemotherapy. After the peripherally inserted central catheter insertion, the chest X-ray and computed tomography showed that the catheter was located in the persistent left superior vena cava. After an assessment of the persistent left superior vena cava and the catheter tip position, the peripherally inserted central catheter remained in th...
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Authors: Corcione S, Pensa A, Castiglione A, Lupia T, Bortolaso B, Romeo MR, Stella M, Rosa FG Abstract Burn patients are at high risk of infections due to severe impairment of immunity and loss of skin barrier function. We aimed to describe the epidemiology, incidence and risk factors for infection in a cohort of burns patients. Two hundred patients were retrospectively enrolled and subdivided into infected (N = 81) and uninfected groups (N = 119). The cumulative prevalence of infections was 27% on day 7 and 43.8% on day 28. Skin and soft tissue infections (32%) were the most frequent. ...
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
ConclusionsThe administration of appropriate antibiotic therapy for ≤7 days may be as safe and effective as longer courses in episodes of GNB CRBSI once the CVC has been removed.
Source: Journal of Antimicrobial Chemotherapy - Category: Microbiology Source Type: research
We present our prospective study of chemoport implantation by external jugular vein cutdown technique. We studied 100 patients who underwent chemoport insertion over a span of 3  years for various solid and haematological malignancies via external jugular vein cutdown method. Outcomes such as type of disease, anaesthesia, choice of venous access, catheter tip position, length of the procedure, time to start chemotherapy and morbidity data were analysed. The Hundred /100 in travenous devices were implanted in 66% females and 33% males. Most common indication was breast cancer (64% of patients). A total of 80% of patien...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
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