Vaccarin hastens wound healing by promoting angiogenesis via activation of MAPK/ERK and PI3K/AKT signaling pathways in vivo.

CONCLUSIONS: The present study was the first to demonstrate that vaccarin is able to induce angiogenesis and accelerate wound healing in vivo by increasing expressions of p-Akt, p-Erk and p-bFGFR. This process is mediated by MAPK/ERK and PI3K/AKT signaling pathways.
PMID: 32049183 [PubMed - in process]

Source: Acta Cirurgica Brasileira - February 13, 2020 Category: Surgery Authors: Hou B, Cai W, Chen T, Zhang Z, Gong H, Yang W, Qiu L Tags: Acta Cir Bras Source Type: research