Autonomic Dysfunction in Guillain –Barré Syndrome Puts Patients at Risk

Source: Neurocritical Care - Category: Neurology Source Type: research

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Some patients with COVID-19 are also presenting with neurologic disorders, including encephalopathy, stroke, Guillain-Barre syndrome and more. What it means, however, is at this point unclear.Medscape Medical News
Source: Medscape Emergency Medicine Headlines - Category: Emergency Medicine Tags: Neurology & Neurosurgery News Source Type: news
Publication date: Available online 1 April 2020Source: The Lancet NeurologyAuthor(s): Hua Zhao, Dingding Shen, Haiyan Zhou, Jun Liu, Sheng Chen
Source: The Lancet Neurology - Category: Neurology Source Type: research
In this study, we performed a head-to-head comparison of the immune response induced by different EZIKV-based vaccine candidates in mice. We compared different platforms (DNA, recombinant protein), adjuvants (poly (I:C), CpG ODN 1826) and immunization strategies (homologous, heterologous). The hierarchy of adjuvant potency showed that poly (I:C) was a superior adjuvant than CpG ODN. While poly (I:C) assisted immunization reached a plateau in antibody titers after two doses, the CpG ODN group required an extra immunization dose. Besides, the administration of poly (I:C) induced higher EZIKV-specific cellular immune response...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Abstract Campylobacter jejuni is considered to be the most common bacterial cause of human gastroenteritis worldwide. C. jejuni can cause bloody diarrhoea, fever and abdominal pain in humans along with post-infectious sequelae such as Guillain-Barré syndrome (a paralytic autoimmune complication). C. jejuni infections can be fatal, particularly among young children. C. jejuni are distributed in most warm-blooded animals, and therefore the main route of transmission is generally foodborne, via the consumption and handling of meat products (particularly poultry). C. jejuni is microaerophilic and oxygen-sensiti...
Source: Microbiology - Category: Microbiology Authors: Tags: Microbiology Source Type: research
The recreational use of nitrous oxide (N2O) is increasing in festivals, university parties, clubs, private residences, and parks. The abuse of N2O has serious complications of the central and peripheral nervous system. In this article...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Publication date: Available online 23 March 2020Source: Journal of Clinical NeuroscienceAuthor(s): Monojit Debnath, Madhu Nagappa, Debprasad Dutta, Pinku Mani Talukdar, Manjula Subbanna, Venkataram Shivakumar, Rahul Wahatule, Sanjib Sinha, Parayil Sankaran Bindu, Sundar Periyavan, G.S. Umamaheswara Rao, Malathi Anil Kumar, Arun B. Taly
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Conclusions: Preliminary literature suggests that FMT may be a promising treatment option for several neurological disorders. However, available evidence is still scanty and some contrasting results were observed. A limited number of studies in humans have been performed or are ongoing, while for some disorders only animal experiments have been conducted. Large double-blinded randomized controlled trials are needed to further elucidate the effect of FMT in neurological disorders.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Dengue virus (DENV) and Zika virus (ZIKV) are two mosquito-borne flaviviruses afflicting nearly half of the world population. Human infection by these viruses can either be asymptomatic or manifest as clinical diseases from mild to severe. Despite more cases are presented as self-limiting febrile illness, severe dengue disease can be manifested as hemorrhagic fever and hemorrhagic shock syndrome, and ZIKV infection has been linked to increased incidence of peripheral neuropathy Guillain-Barre syndrome and central neural disease such as microcephaly. The current prevention and treatment of these infectious diseases are eith...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
We describe the case of a 7-year-old boy who presented with diplopia, speech difficulty, dysphagia, gait disturbance, and difficulty in eyeball movements since 5 days. On examination, the child was having ataxia, areflexia, ophthalmoplegia, drooling of saliva, dysphonia, and absent gag reflex. MFS and brain stem encephalitis were kept as the differential diagnoses. The patient improved gradually over 3 weeks, following a treatment with intravenous immunoglobulin.
Source: Journal of Pediatric Neurosciences - Category: Neuroscience Authors: Source Type: research
Outside academia, community and rural medical centers often rely on clinical signs and symptoms for early intervention, as means of gathering objective data may be unavailable, or the reliance of biological testing may take too long to return. Continued reporting of atypical presentations is therefore necessary for broadening clinical recognition of such cases. AbstractOutside academia, community and rural medical centers often rely on clinical signs and symptoms for early intervention, as means of gathering objective data may be unavailable, or the reliance of biological testing may take too long to return. Continued repo...
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
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