Visible-light-initiated malic acid-promoted cascade coupling/cyclization of aromatic amines and KSCN to 2-aminobenzothiazoles without photocatalyst

Publication date: Available online 8 February 2020Source: Chinese Chemical LettersAuthor(s): Wei-Bao He, Lan-Qing Gao, Xin-Jie Chen, Zhi-Lin Wu, Ying Huang, Zhong Cao, Xin-Hua Xu, Wei-Min HeAbstractBy using ambient air as the oxidant and malic acid as the promoter, a practical method for the preparation of 2-aminobenzothiazoles through visible-light-initiated cascade reaction of aromatic amines and KSCN in eco-friendly bis(methoxypropy)ether under metal-, hazardous additive-, photocatalyst-free conditions was established.Graphical abstractA simple and practical method for the synthesis of 2-aminobenzothiazoles through visible-light-initiated malic acid-promoted cascade coupling/cyclization of aromatic amines and KSCN with ambient air as an oxidant in eco-friendly bis(methoxypropy) ether at ambient temperature was developed.

Source: Chinese Chemical Letters - February 9, 2020 Category: Chemistry Source Type: research