Differential Impact of Weight Loss and Glycemic Control on Inflammasome Signaling.

CONCLUSIONS: Plasma IL-1β and caspase-1 levels were inversely correlated with IR. Caspase-1 levels normalized after weight loss, whereas IL-1β normalized only in people without T2D, suggesting the persistence of a systemic inflammatory condition in people with T2D.
PMID: 32020775 [PubMed - as supplied by publisher]

Source: Obesity - February 4, 2020 Category: Eating Disorders & Weight Management Authors: Antonioli L, Moriconi D, Masi S, Bottazzo D, Pellegrini C, Fornai M, Anselmino M, Ferrannini E, Blandizzi C, Taddei S, Nannipieri M Tags: Obesity (Silver Spring) Source Type: research