Temporal stability of driver injury severities in animal-vehicle collisions: A random parameters with heterogeneity in means (and variances) approach
This study investigates the determinants of driver injury severity in animal-vehicle collisions while systematically accounting for unobserved heterogeneity in the data by using three methodological approaches: mixed logit model, mixed logit model with heterogeneity in means, and mixed logit model with heterogeneity in means and variances. Using the data from Washington state from January 1, 2012 to December 31, 2016, a wide range of factors that could potentially affect the injury severity of drivers were examined. Moreover, the temporal stability and transferability of the models were investigated through a series of likelihood ratio tests. Marginal effects were also used to study the temporal stability of the explanatory variables. Model estimation results show that many parameters can potentially increase the likelihood of severe injuries in Animal-vehicle crashes including freeways/expressways, daylight crashes, early morning crashes, dry road surface and clear weather condition. Moreover, the model estimation results show that accounting for the heterogeneity in the means (and variances) of the random parameters can improve the overall fit of the model. Some variables showed relatively similar marginal effects among different methodological approaches while some others showed different marginal effects upon the application of different methods. With regard to temporal stability of explanatory variables, the findings of this study show how underestimating the temporal st...
Publication date: Available online 10 July 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): V. Saravanan, S.S. Murugan, T.S. Kumaravel
Publication date: June–July 2020Source: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volumes 854–855Author(s):
Publication date: Available online 10 July 2020Source: Trends in GeneticsAuthor(s): David S. Wendler
Publication date: Available online 11 July 2020Source: Gene Expression PatternsAuthor(s): Roberto Rodríguez-Morales, Viveca Vélez-Negrón, Aranza Torrado-Tapias, Gaurav Varshney, Martine Behra
Publication date: Available online 10 July 2020Source: Revista Clínica Española (English Edition)Author(s): J.J. Hijona Elósegui, A.L. Carballo García, A.C. Fernández Risquez, M. Bermúdez Quintana, J.F. Expósito Montes
In this study, cynomolgus macaque UGT3A1, UGT3A2, and UGT8A1 cDNAs were isolated and characterized. Amino acid sequences deduced from cynomolgus UGT3A1, UGT3A2, and UGT8A1 cDNAs were highly identical with their human orthologs (93, 96, and 99%, respectively) and were closely clustered in a phylogenetic tree. In the genome, cynomolgus UGT3A and UGT8A genes were located in the regions corresponding to those of their human orthologs. Among the 10 tissue types analyzed, expression of cynomolgus UGT3A1 and UGT3A2 mRNAs was detected in liver, kidney, and testis; the UGT3A1 and UGT3A2 mRNAs were most abundant in liver and testis,...
Publication date: October 2020Source: Safety Science, Volume 130Author(s): Fei Tang, Zunxin Zhao, Kun Zhao
Publication date: Available online 10 July 2020Source: Safety ScienceAuthor(s): Paul Lindhout, Genserik Reniers
Publication date: Available online 11 July 2020Source: Safety and Health at WorkAuthor(s): Saija Hyvönen, Jouni Lohi, Tamara Tuuminen
Publication date: November 2020Source: Urology Case Reports, Volume 33Author(s): Gina T. Baaklini, Misty J. Thompson, Kevin J. Krauland, Daniel R. Walker, Steven J. Hudak