αIIb-integrin (CD41) associated with blood eosinophils is a potential biomarker for disease activity in eosinophilic esophagitis

Capsule summary: After EoE treatment, association of platelets with blood eosinophils, as reported by CD41, predicted esophageal eosinophil count. Percentage CD41+ circulating eosinophils is a potential non-invasive biomarker for EoE disease activity.

Source: Journal of Allergy and Clinical Immunology - January 27, 2020 Category: Allergy & Immunology Authors: Mats W. Johansson, Elizabeth M. McKernan, Paul S. Fichtinger, Evelyn L. Angulo, Jennifer L. Bagley, Kristine E. Lee, Michael D. Evans, Luis D. Lomeli, Deane F. Mosher, Shelly M. Cook, Eric A. Gaumnitz, Sameer K. Mathur Source Type: research