Association of complicated gallstone disease in pregnancy and adverse birth outcomes

Publication date: Available online 24 January 2020Source: The American Journal of SurgeryAuthor(s): Jason M. Bowie, Richard Y. Calvo, Vishal Bansal, Lyndsey E. Wessels, William J. Butler, C. Beth Sise, Jennifer G. Shaw, Michael J. SiseAbstractBackgroundComplicated gallstone disease (CGD) is a common condition requiring intervention during pregnancy to avert adverse birth outcomes (ABO).MethodsCohort study using the California OSHPD 2007–2014 database. Records of pregnant patients were analyzed for gallbladder calculus within four months of delivery. Biliary system interventions were evaluated as the primary exposure.ResultsOf 7,597 patients, those with CGD had a greater likelihood of biliary system procedures than those with uncomplicated gallstone disease (36.6% vs. 2.5%, p 
Source: The American Journal of Surgery - Category: Surgery Source Type: research

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ConclusionAdministrative claim data can be analyzed through Formal Concept Analysis in order to classify trajectories of care. This approach permits to quantify expected postoperative complications and to identify unexpected events.
Source: Obesity Surgery - Category: Surgery Source Type: research
Jo Lisgo was pregnant with her first child when what began as heartburn escalated into something that now, as a mother of two, she says felt even more painful than childbirth.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conclusions: ERCP done by experienced endoscopists is a safe procedure during pregnancy. Radiation-free techniques appear to reduce the rates of nonpregnancy-related complications, but not of fetal and pregnancy-related complications.
Source: The Saudi Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
Authors: Sticova E, Jirsa M Abstract ATP-binding cassette (ABC) subfamily B member 4 (ABCB4), also known as multidrug resistance protein 3 (MDR3), encoded by ABCB4, is involved in biliary phospholipid secretion, protecting hepatobiliary system from deleterious detergent and lithogenic properties of the bile. ABCB4 mutations altering canalicular ABCB4 protein function and expression may have variable clinical presentation and predispose to several human liver diseases. Well-established phenotypes of ABCB4 deficit are: progressive familial intrahepatic cholestasis type 3, gallbladder disease 1 (syn. low phospholipid ...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
CONCLUSIONS: forty-eight variants were identified in five genes including ABCB4, ABCB11, ATP8B1, SLC4A2 and GPBAR1, twenty-five of which were novel. This study expands the phenotypic and mutational spectrum in genes involved in bile acid homeostasis and highlights the genetic and phenotypic heterogeneity in patients with inherited liver disorders. PMID: 31538484 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
The objective of this study was to determine whether ICP is associated with specific long ‐term comorbidity.Material and methodsThe study population comprised 571 women with ICP in at least one pregnancy who were compared with 1333 pregnant women without ICP during 1969 ‐1988 at Tampere University Hospital, Finland. The cohort's follow‐up time was 44 years. All ICD‐10 classification discharge diagnoses were examined for the women in the ICP group from 1998 to 2013 and ICD‐10 diagnoses from outpatient care from 1969 to 2013.ResultsAt least one disease of the digestive system had been diagnosed in 50.4% (288/5...
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
The objective of this study was to determine whether ICP is associated with specific long ‐term co‐morbidity.Material and methodsThe study population comprised 571 women with ICP in at least one pregnancy who were compared with 1333 pregnant women without ICP during the years 1969 –1988 at Tampere University Hospital, Finland. The cohort's follow‐up time was 44 years. All ICD‐10 classification discharge diagnoses were examined for the women in the ICP group from 1998 to 2013 and ICD‐10 diagnoses from outpatient care from 1969 to 2013.ResultsAt least one disease of the digestive system had been diagnosed in ...
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Original Research Article Source Type: research
Reproductive-aged women constitute a substantial proportion of patients who undergo weight-loss procedures. While the risk of gallstone disease following such procedures has been addressed extensively; the impact of pregnancy on gallstone disease following bariatric procedures has not been reported.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
Reproductive-aged women constitute a substantial proportion of patients who undergo weight loss procedures. While the risk of gallstone disease after such procedures has been addressed extensively, the impact of pregnancy on gallstone disease after bariatric procedures has not been reported.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original article Source Type: research
CONCLUSION: Acute biliary pancreatitis related to pregnancy is not limited to pregnant women, and the incidence of these cases was greater than expected. Acute biliary pancreatitis related to pregnancy can be successfully managed with conservative treatment because it usually has a mild to moderate clinical course. However, the surgeon should keep an early cholecystectomy in mind for patients other than those in the first trimester. PMID: 31135938 [PubMed - in process]
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - Category: Emergency Medicine Authors: Tags: Ulus Travma Acil Cerrahi Derg Source Type: research
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