Insys Founder Gets 5 ½ Years in Prison in Opioid Kickback Scheme

The company executive, John Kapoor, was accused of bribing doctors and misleading insurers to increase sales of a highly addictive painkiller.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Kapoor, John Burlakoff, Alec Babich, Michael L Insys Therapeutics Inc Subsys Opioids and Opiates Fentanyl Pain-Relieving Drugs Racketeering and Racketeers Frauds and Swindling your-feed-healthcare Source Type: news

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Authors: Hanna MN, Chambers C, Punyala A, Iqbal A, Singh B, Oruc C, Prakash P, Prajapati Y, Wang Y, Amery Ai Z, Shechter R, Speed TJ, Koch CG, Williams K Abstract The use of opioid analgesics for pain management has increased dramatically over the past decade, with corresponding increases in negative sequelae including overdose and death. Physicians, policymakers, and researchers are focused on finding ways to decrease opioid use and overdose. This crisis calls for a coordinated response that includes the entire healthcare sector. In this work, the authors lay out a blueprint for such a response at the level of the...
Source: Journal of Opioid Management - Category: Addiction Tags: J Opioid Manag Source Type: research
CONCLUSION: Overall, PP patients felt the benefits of opioid use outweighed the risks, and using opioid medication sig-nificantly improved their quality of life. This may be partly due to the poor efficacy of other nonprescription medications and complementary therapies in managing PP beyond short-term relief. PMID: 32091612 [PubMed - as supplied by publisher]
Source: Journal of Opioid Management - Category: Addiction Tags: J Opioid Manag Source Type: research
This study aimed to explore health professionals' perspectives regarding opioid use for cancer patients in Qatar. Eight focus groups were conducted with physicians, pharmacists, and nurses. An eight-question topic guide framed discussions and targeted contextual barriers and cultural beliefs. Focus groups were audio-recorded and transcribed verbatim. Thematic analysis was used to identify the following themes: narcotic use process, patient-related factors, and healthcare professional-related factors. Laws and regulations were identified as major barriers to appropriate narcotic access, prescribing, and administration. Gove...
Source: Journal of Pain and Palliative Care Pharmacotherapy - Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
NCCIH Integrative Medicine Research Lecture Series The series provides overviews of the current state of research and practice involving complementary health approaches and explores perspectives on the emerging discipline of integrative medicine. Dr. Garland is a Distinguished Endowed Chair in Research, Professor and Associate Dean for Research College of Social Work; Director, Center on Mindfulness and Integrative Health Intervention Development (C-MIIND); Associate Director of Integrative Medicine, Supportive Oncology Program, Huntsman Cancer Institute at The University of Utah. Dr. Garland will describe development and ...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
Ask a smoker what they get out of cigarettes and they are likely to talk about pleasure, contentment, and an overall good feeling. Nicotine, the active ingredient in cigarettes, is a stimulant. Used in low doses like those delivered by combustible cigarettes, stimulants activate the nervous system, resulting in enhanced arousal and alertness. Nicotine binding in the limbic system — the part of the brain that houses the pleasure and reward center — releases dopamine, resulting in feelings of euphoria. These effects combine to give smokers a boost in their mood. In this context, new research from a team at Harvar...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Addiction Adolescent health Mental Health Smoking cessation Source Type: blogs
CONCLUSIONS: Given increasing rates of opioid addiction and death, viable solutions are universally needed. Successful intervention measures should be widely shared between military, veteran, and civilian healthcare and public health communities. Increased collaboration between these groups could inculcate successful programs to prevent and decrease opioid use. Results received from recent military and veterans' programs for prescription and electronic medical record (EMR) monitoring and data sharing may also prove useful for civilian healthcare providers and hospital systems. Future evaluations from ongoing federally fund...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
“I didn’t get to grow up and pull away from her and bitch about her with my friends and confront her about the things I’d wished she’d done differently and then get older and understand that she had done the best she could and realize that what she had done was pretty damn good and take her fully back into my arms again. Her death had obliterated that. It had obliterated me. It had cut me short at the very height of my youthful arrogance. It had forced me to instantly grow up and forgive her every motherly fault at the same time that it kept me forever a child, my life both ended and begun in that p...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Family Grief and Loss daughters grieving motherless Source Type: blogs
In conclusion, Trx-1 may be very promising for clinical therapy of morphine addiction in the future.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Abstract The 5-HT1A and 5-HT1B serotonin receptors are abundantly expressed in the CNS and constitute validated as well as putative drug targets in a variety of psychiatric and cognitive disorders, alcoholism/addiction, pain and migraine. In the present study we have characterized the functional properties of human 5-HT1A and 5-HT1B stably co-expressed with the human G-protein-activated inwardly rectifying K+ channel 2 (GIRK2) in HEK293 cells in the fluorescence-based FLIPR® Membrane Potential Blue (FMP) assay. Serotonin and other agonists induced robust decreases in fluorescence levels in the 5-HT1A/GIRK2- an...
Source: Biochemical Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Biochem Pharmacol Source Type: research
This study provides a detailed map of oprm1 localization in the brain, which includes previously unreported oprm1 in the habenula of teleost. Presence of oprm1 in multiple brain sites implies multiple action targets of morphine and potential brain functions which could include reward, cognitive and negative emotions.
Source: Frontiers in Neuroanatomy - Category: Neurology Source Type: research
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