Assessment of Structural and Functional Comparability of Biosimilar Products: Trastuzumab as a Case Study

ConclusionsOverall, the results indicated general similarity with respect to structure and function, but we found variations with respect to size heterogeneity, charge heterogeneity, and glycosylation pattern in each of the biosimilars.
Source: BioDrugs - Category: Drugs & Pharmacology Source Type: research