Identification and functional characterization of a novel heterozygous missense variant in the LPL associated with recurrent hypertriglyceridemia ‐induced acute pancreatitis in pregnancy
ConclusionThis report describes the first identification and functional characterization of a heterozygous variant in theLPL that predisposed to recurrent HTG ‐APIP. Our findings confirm a major genetic contribution to the etiology of individual predisposition to HTG‐APIP.
We have read the article titled “Critical pancreatitis management associated with hypertriglyceridemia in pregnancy in emergency service” published by Satılmış et al.  with great interest. We thank the authors for this informative and successful manuscript. We also would like to mention a few important points about plasm a exchange therapy (plasmapheresis/apheresis) in acute pancreatitis.
Acute pancreatitis is a pregnancy complication potentially lethal for both the mother and fetus, occurring most frequently in the third trimester or early postpartum. Hypertriglyceridemia may be the cause of i...
The objective of this study is to better understand the complications associated with acute pancreatitis in pregnancy.
The dangers of alcohol begin at the first sip of the first drink. Although most responsible drinking habits shouldn’t be cause for major concern, everyone who drinks runs the risk of encountering the negative effects of alcohol. The Dietary Guidelines for Americans defines moderate drinking as up to 1 drink per day for women and up to 2 drinks per day for men. A single drink is considered as: 12 ounces of beer (5% alcohol content) 8 ounces of malt liquor (7% alcohol content) 5 ounces of wine (12% alcohol content) 1.5 ounces of 80-proof (40% alcohol content) distilled spirits or liquor (e.g., gin, rum, vodka, ...
A 29-year-old woman, G2P1001, presented with irregular vaginal bleeding for 7 weeks 2 days and a serum beta-hcg level of 3000 mIU/mL. The patient had previously undergone two open abdominal surgeries for necrotizing pancreatitis four years ago. Abdominal and bimanual examinations revealed the prior inverted U-shaped surgical scar (Figure 1) and a normal size uterus without any tenderness or pain.
Aspects concerning patient adherence to anti-TNFα therapy in psoriasis: A decade of clinical experience. Exp Ther Med. 2019 Dec;18(6):4987-4992 Authors: Mocanu M, Toader MP, Rezus E, Taranu T Abstract Non-adherence to psoriasis treatment has an important impact in controlling chronic disease evolution and the occurrence of systemic comorbidities. Biologic therapy represents a revolutionary treatment, many of the undesirable psychological and socio-economical consequences of conventional topical or systemic therapies being avoided. Nevertheless, the discontinuation of biological therapy may occur ...
CONCLUSIONS: PEX led to a positive maternal outcome in absence of foetal and gestational complications in a case of severe HP in pregnancy. As clinical trials are lacking, case reports still represent the best way to reasonably implement clinical management of this rare but life-threatening disease. PMID: 31818441 [PubMed - in process]
ConclusionsThis consensus by experts from Italian Endocrine and Gynecologic Scientific Societies has edited recommendations derived form the available data and published guidelines of International Scientific Societies.