BPA side effects persist through generations

BPA exposure may activate an immune system response linked to asthma that is passed down through generations, according to a study published in the journal ofProteome Research.Science Daily
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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PMID: 32089229 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
Conclusions: In previously non-active users of asthma maintenance medication subsequently commenced on maintenance therapy, intermittent use was common during the 2-year follow-up despite the potential need for regular use as evidenced by patient HCU and SABD usage patterns. This highlights the need for regular patient assessment and education on medication adherence to ensure appropriateness of prescribing to maintain asthma control. PMID: 32090642 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Conclusion: Coherent trigger domains are readily identified and measured reliably by a Spanish-language ATI version. However, factor structures vary between samples from different Hispanic/Latino cultural and geographic domains. Culturally adapted versions of this instrument are therefore required for Hispanic/Latino population studies. PMID: 32089019 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Publication date: February 2020Source: Trends in Anaesthesia and Critical Care, Volume 30Author(s): Mrs. Haley T. Godwin, Megan L. Fix, Olesya Baker, Troy Madsen, Ron M. Walls, Calvin A. Brown
Source: Trends in Anaesthesia and Critical Care - Category: Anesthesiology Source Type: research
Publication date: Available online 23 February 2020Source: Microbial PathogenesisAuthor(s): Ali Taghipour, Ali Rostami, Mahdi Sepidarkish, Fatemeh GhaffarifarAbstractThere are numerous epidemiological and experimental evidences to suggest that Ascaris lumbricoides infection is a neglected risk factor for development of asthma. For this purpose, we conducted a systematic review and meta-analysis for better understanding of this relationship. Systematic searching (PubMed, Scopus, Web of Science and Google Scholar) was done, up to September 30, 2019 to identify the relevant studies. We applied random-effects meta-analysis mod...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
BackgroundKetotifen is a second ‐generation noncompetitive H1‐antihistamine and mast‐cell stabilizer. It is commonly used to treat or prevent allergic conjunctivitis, asthma, chronic urticaria, anaphylaxis, mast‐cell, and other allergic‐type disorders. However, it has never been studied in aspirin‐exacerbated respirato ry disease (AERD), an aggressive phenotype of chronic rhinosinusitis with nasal polyps, where the mast cell plays a prominent role its pathogenesis.MethodsHuman sinonasal epithelial cells were grown at an air ‐liquid interface (ALI). Ketotifen powder was dissolved in saline to make 4 test solut...
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Omalizumab, an anti-IgE medication approved to treat asthma and hives, significantly reduced children ’s atopic dermatitis severity and improved their quality of life, according to a trial in JAMA Pediatrics.
Source: JAMA - Category: General Medicine Source Type: research
This study evaluated the impact of this program on asthma admissions in the population aged 1 –19 years. In addition, a cost-benefit analysis compared data before and after the introduction of the program.
Source: Respiratory Medicine - Category: Respiratory Medicine Authors: Source Type: research
Emerging findings indicate there is a vital cross-talk between gut microbiota and the lungs, which is known as gut–lung axis. The gut disturbances in lung diseases including allergy, asthma, chronic obstructive pulmonary disease, cystic fibrosis and lung cancer were observed by extensive studies. Investigating how gut microbiota impact other distant organs is of great interest in recent years. Although it has not been fully understood whether the disturbance is the cause or effect of lung diseases, alterations in the gut microbial species and metabolites have been linked to changes in immune responses and inflammatio...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Individuals with life-threatening food allergy (FA) often experience elevated anxiety as they avoid accidental exposure to allergens, modify daily routines, and undergo treatments: In sum, quality of life can be adversely impacted.1-5 Allergists providing diagnostic and treatment services for these patients frequently hear about these psychosocial struggles, however, little is known about the interaction of the medical and psychosocial needs of FA children and families.3 Therefore, this study was conducted to explore the challenges children and families encounter during their FA journey, and factors associated with better ...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
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