Tunnel Vision in a Patient with Polymyalgia Rheumatica.

Tunnel Vision in a Patient with Polymyalgia Rheumatica. J Rheumatol. 2020 Jan;47(1):155-156 Authors: Milchert M, Brzosko M PMID: 31894091 [PubMed - in process]
Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research

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Authors: Ide Y, Yuki T, Taooka Y, Higashi Y, Tachiyama Y Abstract A 30-year-old man was admitted to our hospital because of pain in his proximal extremities. The pain mimicked polymyalgia rheumatica (PMR) and it temporarily improved by a low dose of glucocorticoids, but his symptoms relapsed many times. After six years of glucocorticoid treatment, he developed abdominal pain and ascites, for which he was diagnosed with malignant peritoneal mesothelioma (MPM). His PMR-like symptoms improved with cytoreductive surgery and chemotherapy for MPM. Finally, we diagnosed this PMR-like syndrome to be paraneoplastic syndrome...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Abstract Polymyalgia rheumatica (PMR) is an inflammatory disorder in the elderly and is characterized by pain in the shoulders and lower back. Previous studies from western countries have shown that relapse is frequent; however, there are only a few reports on the relapse rate in Japan. Here we examined the relapse rate, and sought to identify factors that predict recurrence in patients with PMR. Of 110 patients who fulfilled the Bird's criteria for PMR between May 2011 and June 2019, 21 patients were excluded, and the remaining 89 patients were followed up until July 2019. Relapse was defined when clinical sympto...
Source: The Tohoku Journal of Experimental Medicine - Category: Research Authors: Tags: Tohoku J Exp Med Source Type: research
ConclusionDepression is highly prevalent among patients with primary systemic vasculitis and associated with poorer outcomes across a range of measures in studies of small vessel disease. Further studies are needed for depression in medium and large vessel vasculitides.
Source: Rheumatology International - Category: Rheumatology Source Type: research
AbstractPurpose of the ReviewPolymyalgia rheumatica (PMR) is one of the most common inflammatory rheumatologic condition occurring in older adults. It is characterized by proximal pain and stiffness in the shoulders, neck, and/or pelvic girdle in individuals over 50  years of age along with evidence of an intense systemic inflammatory response. Although the above clinical symptoms are very characteristic for the condition, it can be mimicked by other autoimmune, infectious, malignant, and endocrine disorders chief among which are giant cell arteritis (GCA) and elderly-onset rheumatoid arthritis (EORA). Recently, PMR w...
Source: Current Rheumatology Reports - Category: Rheumatology Source Type: research
Source: eMedicineHealth.com - Category: General Medicine Source Type: news
AbstractWe aimed to identify predictors of inadequate response to glucocorticoid (GC) treatment in patients with polymyalgia rheumatica (PMR). We retrospectively studied 32 patients as a derivation cohort and 24 patients as a validation cohort. The patients were divided into two groups according to the response to GC treatment: GC-responders and GC-inadequate responders (GC-IRs). We compared laboratory data and bilateral shoulder ultrasound findings between the groups. Receiver operating characteristic (ROC) analysis was performed to determine the optimal cutoff value of candidate predictors of treatment response; the pred...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Conclusions: Present study demonstrates the potential role of 18F-FDG PET/CT in mapping the distribution of involvement and extent in this diagnostically challenging entity. Additionally 18F-FDG PET/CT helped in identifying coexisting active vasculitis in these subsets of patients. Furthermore, it may be helpful in treatment response evaluation and more prospective studies are needed to establish the same.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Infection/Pulmonary/Outcomes (Poster Session) Source Type: research
We examined the 1998 –2016 US National Inpatient Sample for serious infections in PMR or GCA, namely, opportunistic infections (OI), skin and soft tissue infections (SSTI), urinary tract infection (UTI), pneumonia, and sepsis/bacteremia. Multivariable-adjusted logistic regressions assessed association of the type of i nfection, demographics, comorbidity, and hospital characteristics with healthcare utilization and mortality.ResultsHospitalized with serious infections, those with PMR or GCA were 2 decades older than people without PMR or GCA, and more likely to be female or white or have higher Deyo-Charlson index sco...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
We report the first case of autoimmune pulmonary alveolar proteinosis associated with and preceding myelodysplastic syndrome. AbstractWe report the first case of autoimmune pulmonary alveolar proteinosis (PAP) associated with and preceding myelodysplastic syndrome. A 74 ‐year‐old female with a history of polymyalgia rheumatica presented with six months history of progressive exertional breathlessness. Examination revealed bilateral chest crackles and exertional desaturation. A diagnosis of autoimmune PAP was made based on the presence of autoantibodies to granu locyte‐macrophage colony‐stimulating factor and charac...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
Conclusions: Headache attributed to PMR is a steroid-responsive syndrome which should be considered in an older adult presenting with features of PMR, when the TAB is negative. Diagnostic criteria for headache attributed to PMR are proposed.
Source: The Neurologist - Category: Neurology Tags: Case Report/Case Series Source Type: research
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