Biocompatibility of a polymer-coated membrane possessing a hydrophilic blood-contacting layer: Adsorption-related assessment.

CONCLUSION: This study suggests that albumin is not adsorbed on either acrylate-based copolymer-coated or non-coated membranes, that lysozyme is not adsorbed on either membrane or is adsorbed at a similar rate on both membranes, and that vancomycin is less adsorbed on acrylate-based copolymer-coated membranes. Thus, acrylate-based copolymer coating could inhibit the adsorption of various peptide compounds.
PMID: 31875413 [PubMed - as supplied by publisher]

Source: The International Journal of Artificial Organs - December 24, 2019 Category: Transplant Surgery Authors: Tagaya M, Okano S, Murataka T, Handa H, Ichikawa S, Takahashi S Tags: Int J Artif Organs Source Type: research