Two new hydroperoxy steroids from the South China Sea gorgonian Rumphella sp.

Publication date: Available online 20 December 2019Source: SteroidsAuthor(s): Fang-Zhou Yin, Min Yang, Song-Wei Li, Meng-Jun Wu, Xia-Juan Huan, Ze-Hong Miu, Hong Wang, Yue-Wei GuoAbstractTwo new hydroperoxy steroids, namely, xidaosteroids A and B (1 and 2), along with five known related compounds 3–7, were isolated from the South China Sea gorgonian Rumphella sp.. Their structures were established by extensive spectroscopic analyses and comparison of the spectral data with those reported in the literature. In bioassay, compound 3 showed weak cytotoxicities against SNU-398 and Capan-1 cells.Graphical abstract:
Source: Steroids - Category: Drugs & Pharmacology Source Type: research