Multi-Institutional Evaluation of Inter-rater Agreement of Variant Classification Based on the 2017 AMP, ASCO and CAP Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer

This study demonstrates noteworthy discordances between pathologists for variant classification in solid tumors when using the 2017 AMP/ASCO/CAP guidelines. These findings highlight potential areas for clarification/refinement prior to mainstream clinical adoption.
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research