Peri-procedural Elevated Myocardial Biomarkers Predict Adverse Clinical Outcomes Following Elective Percutaneous Coronary Intervention: A Comprehensive Dose-Response Meta-Analysis of 24 Prospective Studies with 44972 patients.

CONCLUSIONS: We found a positive dose-response relationship between isolated cardiac troponin I and CK-MB with all-cause mortality and elevated cardiac troponin I > 3x or CK-MB > 1x the 99th percentile URL was associated with the increased risk of mortality. PMID: 31829942 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

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Authors: Yoon CH PMID: 31960633 [PubMed]
Source: Korean Circulation Journal - Category: Cardiology Tags: Korean Circ J Source Type: research
We report the case of a 33-year-old woman with no history of coronary risk factors or chest pain who experienced intermittent chest pain at rest for several minutes from 2 PM. At 8 AM the next day, chest pain recurred and persisted for about 1 hour. She was transported to our hospital by ambulance, where electrocardiogram showed ST-elevation in the precordial leads, and blood tests showed elevation of cardiac markers. She was diagnosed with ST-elevation myocardial infarction. Because she was a young woman without any risk factors, coronary spastic angina was suspected. Coronary angiography without intracoronary nitrate adm...
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research
CONCLUSION: The use of energized stiff guidewires to perform ECFC can be of great value for CTO lesions when standard CTO techniques fail. ECFC should only be performed with caution by experienced and high-volume operators to avoid complications. PMID: 31958072 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
Authors: Mirzaee S, Isa M, Thakur U, Cameron JD, Nicholls SJ, Dundon BK Abstract BACKGROUND: Despite the high prevalence of coronary bifurcation lesions in routine interventional cardiology practice, the best strategy for managing this challenging lesion subset remains debatable. Due to potential for complications, the routine practice of side-branch (SB) predilation is controversial. METHODS: An electronic search was performed of online databases up until April 2018 for studies reporting periprocedural angiographic outcomes comparing provisional main-branch stenting with and without SB predilation. Random-effe...
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
Publication date: Available online 22 January 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Giuseppe De Luca, Monica Verdoia, Stefano Savonitto, Luca A. Ferri, Luigi Piatti, Daniele Grosseto, Nuccia Morici, Irene Bossi, Paolo Sganzerla, Giovanni Tortorella, Michele Cacucci, Maurizio Ferrario, Ernesto Murena, Girolamo Sibilio, Stefano Tondi, Anna Toso, Sergio Bongioanni, Amelia Ravera, Elena Corrada, Matteo MarianiAbstractBackgroundElderly patients are at increased risk of hemorrhagic and thrombotic complications after an acute coronary syndrome (ACS). Frailty, comorbilities and low body weight hav...
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Authors: Parker WAE, Storey RF Abstract Aspirin and P2Y12 inhibitors remain commonly prescribed antiplatelet drugs in the treatment of atherothrombotic conditions. Despite established benefits of dual antiplatelet therapy (DAPT) in the setting of acute coronary syndromes, there remains residual ischemic risk in this group and the problem of bleeding complications is an ongoing issue. DAPT with aspirin and ticagrelor has now been studied in other patient groups such as those with concurrent diabetes and stable coronary artery disease, and those undergoing elective percutaneous coronary intervention (PCI). Recent tri...
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
AbstractThe prognostic value of the geriatric nutritional risk index (GNRI) in patients undergoing percutaneous coronary intervention (PCI) with rotational atherectomy (RA) remains unknown. Therefore, we aimed to clarify whether the GNRI could predict major adverse cardiac events (MACE) in patients undergoing PCI with RA. A total of 206 patients who underwent PCI with RA from January 2009 to December 2017 were retrospectively tracked. The patients were divided into 2 groups based on the GNRI value on admission. MACE comprised all-cause death, target lesion revascularization (TLR), target vessel revascularization (TVR), and...
Source: Heart and Vessels - Category: Cardiology Source Type: research
Elderly patients are at increased risk of hemorrhagic and thrombotic complications after an acute coronary syndrome (ACS). Frailty, comorbilities and low body weight have emerged as conditioning the prognostic impact of dual antiplatelet therapy (DAPT). The aim of the present study was to investigate the prognostic impact of body mass index (BMI) on clinical outcome among patients included in the Elderly-ACS 2 trial, a randomized, open-label, blinded endpoint study comparing low-dose (5mg) prasugrel vs clopidogrel among elderly patients with ACS.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Source Type: research
Cardiac rehabilitation (CR) is a recommended treatment strategy for multiple populations to elicit well-established improvements in functional capacity, quality of life, and long-term outcomes.1 –6 Risk reduction has been shown in both all-cause and cardiovascular mortality with CR participation following percutaneous coronary intervention (PCI), myocardial infarction (MI), coronary artery bypass graft (CABG) surgery, and ventricular assist device implantation.1,7–10 More recently, long -term major adverse cardiac events (MACE) have also been investigated in these populations as a method of identifying high-ris...
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research
Although the relationship between cancer and all the secondary events following a percutaneous coronary intervention (PCI) should represent a priority for clinicians and health professionals, the knowledge on this issue is still limited. Possible reasons for this discrepancy are mainly related to the common exclusion of cancer patients from the majority of PCI clinical trials and, consequently, from cardiovascular disease (CVD) national registries.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
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