Development of a new methylation ‐based fetal fraction estimation assay using multiplex ddPCR

ConclusionBy employing a set of well ‐characterized DMRs, we developed a SNP‐, sex‐ and ploidy‐independent methylation‐based multiplex ddPCR assay for accurate fetal fraction estimation.

Source: Molecular Genetics & Genomic Medicine - December 9, 2019 Category: Genetics & Stem Cells Authors: Marios Ioannides, Achilleas Achilleos, Skevi Kyriakou, Elena Kypri, Charalambos Loizides, Kyriakos Tsangaras, Louiza Constantinou, George Koumbaris, Philippos C. Patsalis Tags: ORIGINAL ARTICLE Source Type: research