Utility of hairless rats as a model for predicting transdermal pharmacokinetics in humans.

Conclusions: In vivo skin absorption data from HWY hairless rats help predict human concentration profiles for lipophilic compounds. However, the data underestimate human absorption of hydrophilic compounds. PMID: 31814485 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31814485?dopt=Abstract

Source: Xenobiotica - December 8, 2019 Category: Research Authors: Yamamoto S, Sano N, Fukushi C, Arai Y, Karashima M, Hirabayashi H, Amano N Tags: Xenobiotica Source Type: research