Principles and Practice of Oral Rehydration

This report reviews the scientific rationale and modifications of ORS and barriers to universal application.Recent FindingsSolutions with osmolality and electrolyte composition different from original ORS for routine and unique pathophysiology such as in malnutrition have met with varying success. Following the conceptual rationale of sodium-glucose cotransportation to facilitate water absorption, other cotransporters and formulations have been explored with the aim to improve ORS efficacy and acceptance.SummaryORS remains the anchor of acute watery diarrhea and dehydration management worldwide. Despite development of different formulations, the current standard solution is the mainstay of treatment for nearly all situations. Efforts to improve oral hydration solution and to increase acceptance and usage are ongoing.
Source: Current Gastroenterology Reports - Category: Gastroenterology Source Type: research