Association of Body Fluid Distribution With Obstructive Sleep Apnea in Pregnant Women With Body Mass Index ≥ 40 kg/m2

Conditions:   Apnea, Obstructive Sleep;   Obesity Intervention:   Device: Bioelectrical Impedance Analysis (BIA) Sponsor:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Right now, one in 12 children and adolescents in the US are severely obese. If that isn’t startling enough, consider this: among 12-to-15-year-olds, that number jumps to one in 10 — and among 16-to-19-year-olds, it is one in seven. According to the American Academy of Pediatrics (AAP), the best hope for many of these youths may be bariatric surgery. Bariatric surgery is surgery that helps with weight loss by making the stomach smaller and making other changes in the digestive system. It’s jarring to think about doing irreversible surgery on an adolescent — or a child, as the AAP discourages age limi...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Adolescent health Children's Health Diabetes Diet and Weight Loss Parenting Source Type: blogs
Authors: Taylor CR, Dominguez JE, Habib AS Abstract Obesity is a significant global health problem. It results in a higher incidence of complications for pregnant women and their neonates. Cesarean deliveries are more common in obese parturients as well. The increased burden of comorbidities seen in this population, such as obstructive sleep apnea, necessitates antepartum anesthetic consultation. These patients pose unique challenges for the practicing anesthesiologist and may benefit from optimization prior to delivery. Complications from anesthesia and overall morbidity and mortality are higher in this population...
Source: Local and Regional Anesthesia - Category: Anesthesiology Tags: Local Reg Anesth Source Type: research
Conditions:   Apnea, Obstructive Sleep;   Obesity Intervention:   Device: Bioelectrical Impedance Analysis (BIA) Sponsor:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study evaluated the validity of existing OSA screening tools in a cohort of extremely obese pregnant women [body mass index (BMI) ≥40 kg/m2] and determined what screening factors were most strongly associated with OSA in this cohort.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mechanisms, Equipment, Hazards Source Type: research
Conclusions:Modeling neck circumference while allowing for differences by Mallampati class showed a nearly threefold increase in the risk of SDB with increasing neck circumference in women with Mallampati class 1. Other potential sites of airway obstruction need to be investigated in future research.Citation:Bourjeily G, Chambers A, Salameh M, Bublitz MH, Kaur A, Coppa A, Risica P, Lambert-Messerlian G. Anthropometric measures and prediction of maternal sleep-disordered breathing.J Clin Sleep Med. 2019;15(6):849–856.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
We examined the validity of the STOP-Bang questionnaire and a modified STOP-Bang questionnaire to screen for obstructive sleep apnea (OSA) in women with obesity during the second trimester of pregnancy.Methods:Ninety-nine pregnant women age 18 years or older with body mass index≥ 40 kg/m2 completed the STOP-Bang questionnaire during their second trimester. The number of oxygen desaturation events (≥ 4% from baseline) was measured using overnight pulse oximetry, with OSA defined as≥ 5 events/h. A Modified STOP-Bang score was derived by replacing the“Tired” item with Epworth Sleepiness Scale score≥ 10...
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
Purpose of review With new medical technologies and changing life styles, maternal demographics has changes and consequently older and sicker women are becoming pregnant. In this review, we present these different high-risk parturient populations, which were once considered rare for the practicing obstetric anesthesiologist. Recent findings With lifestyle and medical advances, older and sicker women are getting pregnant. Older women are more prone to pregnancy complications. Cancer survivors are becoming pregnant and more pregnant women are being diagnosed with cancer. Previous neurological and cardiac conditions con...
Source: Current Opinion in Anaesthesiology - Category: Anesthesiology Tags: OBSTETRIC AND GYNECOLOGICAL ANESTHESIA: Edited by Emilia Guasch and Manuel Wenk Source Type: research
Abstract PURPOSE: Often unrecognized, obstructive sleep apnea (OSA) worsens over pregnancy and is associated with poorer perinatal outcomes. Pregnant women with obesity are known to have higher insulin resistance (IR), elevated glucose/lipid profiles, fetal overgrowth and OSA yet the association between OSA in late pregnancy and metabolic biomarkers remains poorly understood. We tested the novel hypothesis that OSA in pregnant women with obesity is positively correlated with 24-hour patterns of glycemia and IR despite controlling for diet. METHODS: Pregnant women with obesity (32-34 wks gestation; BMI 30-40 k...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
(Anesth Analg. 2018;127:1167–1177) Sleep-disordered breathing (SDB) is often comorbid with obesity; among obese pregnant women, 15% to 20% have obstructive sleep apnea (OSA), and prevalence increases with body mass index (BMI). Untreated OSA has been associated with a range of cardiovascular, pulmonary, and metabolic comorbidities. The authors of this review discussed pregnancy as a vulnerable period for the development or worsening of OSA, associations between OSA and adverse maternal and fetal outcomes, current screening modalities for OSA in pregnancy, and current recommendations regarding peripartum management of OSA.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Editorials and Reviews Source Type: research
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