The Comparative Effects of Ticagrelor and Clopidogrel on Arterial Injury and In-Stent Restenosis and Thrombosis of Carotid Artery in Atherosclerotic Rabbits

Introduction - Carotid artery angioplasty and stenting (CAS) is expanding as a method to treat carotid artery disease worldwide. Until now a combination of aspirin and clopidogrel has been used pre and post CAS. Ticagrelor, a P2Y (12) inhibitor, has an important role in coronary artery angioplasty. There is lack of evidence about the impact of ticagrelor on carotid artery disease and CAS. Our aim was the comparative evaluation of ticagrelor and clopidogrel on carotid balloon-injury and in-stent restenosis (ISR) and thrombosis in rabbits.

Source: European Journal of Vascular and Endovascular Surgery - November 30, 2019 Category: Surgery Authors: Nikolaos P. Kadoglou, Marianna Stasinopoulou, Triantafyllos Giannakopoulos, Anastasios Papapetrou, Costis Dimitriou, Anthi Travlou, Efrosyni Merkouri, Nikolaos Kostomitsopoulos, Christos Liapis Source Type: research