Meet 3 British Columbians shattering stereotypes about their disabilities
A blind artist, a motivational speaker who can’t speak and a young mom with arthritis: these are just three of the British Columbians shattering the stereotypes by simply living their lives.
CONCLUSIONS: Overlapping SS is associated with a lower probability of reaching ultrasound remission and no disability in RA patients. HCQ may still be the mainstream of clinical decision making in RA-SS patients. PMID: 33025891 [PubMed - as supplied by publisher]
ARTHRITIS - the most common cause of disability in the UK. Inflammation of the joints can occur in the hip bone. What's the tell-tale sign of the condition?
Conclusion: Anti-CarP antibodies were detected in the sera of a cohort of Belgian RA patients. Moreover, they were also detected in primary SS patients and in JIA patients. In the seronegative subset of RA patients, anti-CarP antibodies showed prognostic value. PMID: 33025839 [PubMed - as supplied by publisher]
Abstract Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that leads to joint destruction and disability. Despite a significant progress in administration of biological agents for RA patients, there is still a need for improved therapy. Intravenous-immunoglobulins (IVIG) , a pooled polyspecific immunoglobulin-G (IgG) extracted from 5,000-20,000 healthy subjects, showed beneficial therapeutic effect in patients with immune-deficiency, sepsis, and autoimmune diseases. The current study aim to investigate the beneficial effect of treatment with IVIG in established collagen induced arthritis in ...
Mortensen E-cigarette use is increasing among young adult never smokers of conventional cigarettes, but the awareness of the factors associated with e-cigarette use in this population is limited. The goal of this work was to use machine learning (ML) algorithms to determine the factors associated with current e-cigarette use among US young adult never cigarette smokers. Young adult (18–34 years) never cigarette smokers from the 2016 and 2017 Behavioral Risk Factor Surveillance System (BRFSS) who reported current or never e-cigarette use were used for the analysis (n = 79,539). Variables associated with curren...
ConclusionOur study can imply that IL ‐17A is a valuable, useful and low‐cost biomarker in detecting early axial SpA changes in asymptomatic and nonradiographic axial SpA (nr‐axial SpA) psoriatic patients that helps early management and prevent progressive axial involvement and disabilities.
CONCLUSION: These results identify clinical features of veterans and service members with mTBI(s) who are at highest risk for pain-related disability. These findings also demonstrate the need to consider mental health and sleep problems in their pain evaluation and treatment approach. PMID: 33007066 [PubMed - as supplied by publisher]
Conclusion: Our study provides a promising nanoplatform for integrating ultrasound-controlled drug release and NIR fluorescence imaging for RA treatment.
CONCLUSION: In this US real-world cohort, most patients had multidomain disease presentations, which was associated with worse disease activity, QOL, and work productivity measures. This study highlights the heterogeneity of PsA and the importance of assessing all PsA domains for optimizing disease management. PMID: 33004532 [PubMed - as supplied by publisher]
This study was undertaken to determine whether treatment with ticagrelor was associated with a lower risk of OA.MethodsWe conducted a 1:2 propensity score –matching analysis using data from 2011–2017 in the Optum Clinformatics Data Mart. Patients who had received either ticagrelor or clopidogrel for ≥90 days were included in our study, and patients with a prior diagnosis of OA or inflammatory arthritis were excluded. OA was identified using Inte rnational Classification of Diseases codes. The primary outcome was the time to diagnosis of OA after treatment with ticagrelor versus clopidogrel.ResultsOur propens...