Acute Fibrinous and Organizing Pneumonia After Lung TransplantAcute Fibrinous and Organizing Pneumonia After Lung Transplant
Get the details of the first case of acute fibrinous and organizing pneumonia triggered by viral infection. Will more cases likely crop up? BMC Pulmonary Medicine
ConclusionPirfenidone and nintedanib do not modulate expression of senescence markers, levels of p ‐SMAD3 or the amount of fibrosis in IPF lungs. Treated patients have less histopathological evidence of acute lung injury at the time of lung transplantation.
CONCLUSION: In a post-LTx setting, LUS represents a clinical novelty as a feasible diagnostic and monitoring tool to identify pathological pulmonary complications in the early post-operative phase. PMID: 30414162 [PubMed - as supplied by publisher]
ConclusionPreoperative thoracic epidural placement provides improved analgesia without increased morbidity following lung transplantation.This article is protected by copyright. All rights reserved.
Independent lung ventilation (ILV) has been successfully used in the management of unilateral lung pathology to improve hypoxemia refractory to conventional mechanical ventilation [1 –3]. ILV via double lumen endotracheal tube (DLT) allows tailoring an independent ventilatory strategy for each lung. It has proved useful in cases of asymmetric lung pathology, including: pulmonary contusion, bronchopleural fistula, unilateral pneumonia, single lung transplantation and reexpansio n pulmonary edema .
Respiratory tract infections remain an important source of morbidity and mortality with pneumonia and influenza serving as the eighth leading cause of death in the United States and the number one cause of death from infectious diseases. Advances in medicine have led to more complex patient populations than in the past, with the advent of novel chemotherapies, immune modulating interventions, and transplantation all creating unique types of immune impairment. Our understanding of the pathogenesis of lung infections had led to the possibility of a uniquely personalized approach to each patient, recognizing the specific path...
We report a case of thoracic air-leak syndrome, an extremely rare complication developed after an episode of organizing pneumonia due to graft-vs-host disease in a 19-year-old male. This unusual non-infectious pulmonary complication occurred 527 days after allogeneic HSCT and led to the patient’s death within 1 month due to cardio-respiratory failure. Herein, we highlight chest-imaging aspects which are typical. Early detection by high-resolution chest CT could improve patient management.
Until recently, lung transplantation was not considered in patients with human immunodeficiency virus (HIV). HIV seropositive patients with suppressed viral loads can now expect long-term survival with the adv...
We describe the use of a decontamination protocol that allowed for successful lung transplantation in a cystic fibrosis patient with necrotizing pneumonia from highly antibiotic-resistant pathogens (Burkholderia and psuedomonas species). This strategy may allow for successful lung transplantation in cystic fibrosis patients with multi-drug resistant infections previously considered non-transplantable.
We describe the use of a decontamination protocol that allowed for successful lung transplantation in a cystic fibrosis patient with necrotizing pneumonia from highly antibiotic-resistant pathogens (Burkholderia and psuedomonas species). This strategy may allow for successful lung transplantation in cystic fibrosis patients with multi-drug resistant infections previously considered non-transplantable. PMID: 30316849 [PubMed - as supplied by publisher]
Authors: Welling JBA, Slebos DJ Abstract The lung volume reduction coil treatment is a minimally invasive bronchoscopic treatment option for emphysema patients who suffer from severe hyperinflation. The treatment is aimed at a large group of patients where lung volume reduction surgery and bronchoscopic lung volume reduction using endobronchial valves are no option, or alternatively, can be offered as a bridge to lung transplantation. The nitinol coil exhibits a shape memory effect and is biologically inert. The lung volume reduction coil procedure is performed in two separate treatment sessions, targeting one lobe...