High street heartburn drugs 'could make people 80% more likely to get stomach bugs'

In a study of 900,000 people, scientists from Sorbonne University in Paris found those who took the acid-reflux medications were 80 per cent more likely to develop acute gastroenteritis.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Conditions:   Acute Gastroenteritis;   Dehydration Intervention:   Sponsor:   University Hospital, Brest Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
FRIDAY, Sept. 18, 2020 -- Coffee, tea, and soda are associated with an increased risk for gastroesophageal reflux (GER) symptoms among middle-aged women, according to a study published in the September issue of Clinical Gastroenterology and...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Conditions:   Acute Gastroenteritis;   Dehydration Intervention:   Sponsor:   University Hospital, Brest Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: LRCC5310 improved clinical symptoms, including diarrhea and Vesikari score, and inhibited viral proliferation in rotaviral gastroenteritis.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
Abstract We compared fecal samples from responders and non-responders to administration of Lactobacillus reuteri DSM 17938. Data for this post hoc analysis were collected from an RCT assessing the efficacy of L. reuteri for the management of acute gastroenteritis. Responders were defined as subjects with diarrhea lasting no longer than 48 h. 44 children (17 responders and 27 non-responders) were analyzed. There were no differences in clinical characteristics and gut colonization between both groups. In the responder group, there were significantly lower levels of five metabolites before beginning of the interventi...
Source: Acta Biochim Pol - Category: Biochemistry Authors: Tags: Acta Biochim Pol Source Type: research
Conclusions: The health policy further increased antibiotic use. On April 2018, a new health policy of paying incentives for not prescribing antibiotics to children with respiratory infection or gastroenteritis was initiated. Further studies are needed whether this new health policy can mitigate the overutilization of healthcare and antibiotic use.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Antimicrobial Reports Source Type: research
Conclusions: The prevalence of erosive tooth wear in enamel and dentin was relatively high in Lithuania; the erosive tooth wear in enamel and dentin combined was 52% among 35- to 44-year-olds, 68% among 45- to 54-year-olds, 67% among 55- to 64-year-olds, and 63% among 65- to 74-year-olds. Lower fluoride level in drinking water was associated with erosive tooth wear in enamel. Male gender, residency in periurban/rural areas, older age, and presence of acid reflux were associated with higher odds, while higher D3MFS scores were associated with lower odds for erosive tooth wear in dentin. These results can be used to plan den...
Source: Caries Research - Category: Dentistry Source Type: research
This study aimed to examine the clinical utility of prolonged wireless reflux monitoring to predict ability to discontinue PPI.
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research
A previously healthy, well-appearing 42-year-old female living in a modern, high-rise apartment in downtown Los Angeles calls 9-1-1 at 5:30 am complaining of worsening of a burning, epigastric pain she had been experiencing for the last three days. She reports associated nausea and non-bloody, non-bilious vomiting, and that she couldn’t manage to get comfortable in bed until she finally decided to call for help at daybreak. During her 9-1-1 call, she reports “pain, like heartburn, that just woke me up again and I had to throw up, … and then I was sweating so much.” Using the Los Angeles Tiered Disp...
Source: JEMS Special Topics - Category: Emergency Medicine Authors: Tags: Exclusive Articles Cardiac & Resuscitation Source Type: news
Authors: Talley NJ Abstract Functional dyspepsia (FD) is a common but under-recognized syndrome comprising bothersome recurrent postprandial fullness, early satiety, or epigastric pain/burning. Epidemiologically, there are two clinically distinct FD syndromes (although these often overlap clinically): postprandial distress syndrome (PDS; comprising early satiety or meal-related fullness) and epigastric pain syndrome. Symptoms of gastroesophageal reflux disease overlap with FD more than expected by chance; a subset has pathological acid reflux. The pretest probability of FD in a patient who presents with classical F...
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
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