Biomarkers to Predict the Response to CRT Biomarkers to Predict the Response to CRT

This article reviews the current evidence on promising biomarkers for predicting response to cardiac resynchronization therapy. Are any sufficiently reliable and sensitive?Europace
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

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We describe a modified snare technique for LV lead placement and evaluate its safety and efficacy in cases when standard methods fail.Methods and ResultsA prospective study was conducted of patients indicated for a CRT implant. When LV lead delivery to the target vessel failed using standard techniques, a modified snare technique was employed. Patients were evaluated every 6 months. From 2015 ‐2019, 566 CRTs were implanted (26.1% female, 72±10.2 years old, follow‐up duration 18.9±15.8 months). The standard LV implant technique failed in 94 cases (16.6%), of which the modified snare technique was successfu...
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ‐ DEVICES Source Type: research
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Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: REVIEW Source Type: research
ConclusionsThe declared outcome of the LBBB groups reflects inevitably the survival outcome of their non ‐ICM patients and not the intended outcome of patients with LBBB. CRT‐D in patients with different aetiologies of cardiomyopathy calls for separate evaluation.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: DEVICE ROUNDS Source Type: research
Journal of Cardiovascular Electrophysiology, EarlyView.
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: LETTER  TO THE EDITOR Source Type: research
Abstract Objectives: It is important to identify super-responders who can derive most benefits from cardiac resynchronization therapy (CRT). We aimed to establish a scoring model that can be used for predicting super-response to CRT. Methods: We retrospectively reviewed 387 CRT patients. Multivariate logistic regression analysis was performed to identify predictors for super-response (defined as an absolute increase in left ventricular ejection fraction of ≥15% at 6-month follow-up) and to create a score model. Multivariate Cox proportional-hazard regression analysis was conducted to assess associations wi...
Source: Cardiology Research and Practice - Category: Cardiology Authors: Tags: Cardiol Res Pract Source Type: research
AbstractPurposeEffectiveness of cardiac resynchronization therapy (CRT) in patients without left bundle branch block (non-LBBB) QRS morphology is limited. Additional selection criteria are needed to identify these patients.MethodsSeven hundred ninety consecutive patients with non-LBBB morphology, who received a CRT-device in 3 university centers in the Netherlands, were selected. Pre-implantation 12-lead ECGs were evaluated on morphology, duration, and area of the QRS complex, as well as on PR interval, left ventricular activation time (LVAT), and the presence of fragmented QRS (fQRS). Association of these ECG features wit...
Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research
Abstract AIMS: To analyze temporal trends (2001 -2017) of Pacemakers (PM) and Implantable Cardioverter-Defibrillators (ICD) procedures in Italy, according to the national Hospital Discharge Database (HDD). METHODS: Frequency and implant rate (IR) in the Italian population were analyzed by age groups (
Source: European Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Eur J Intern Med Source Type: research
ConclusionsSV treatment was related to a lower incidence of cardiac death including HT and LVAD implant in CRT non ‐responders. The optimization of HF management, including SV, should be considered in CRT non‐responders.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Short Communication Source Type: research
This study aims to analyse HF care and in‐hospital outcomes during the pandemic in Germany.Methods and resultsA total of 9452 HF admissions were studied using claims data of 65 Helios hospitals; 1979 in the study period (13 March 30 April 2020) and 4691 and 2782 in two control periods (13 March to 30 April 2019 and 1 January to 12 March 2020). HF admissions declined compared with both control periods by 29 –38%. Cardiac resynchronization therapy was implanted in 0.55% during the study period, 0.32% [odds ratio (OR) 1.66, 95% confidence interval (CI) 0.68–4.04,P = 0.27] in the previous year and 0.43%...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Short Communication Source Type: research
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