Valve interstitial cell-specific cyclooxygenase-1 associated with calcification of aortic valves.

CONCLUSIONS: VIC-specific COX1 overexpression played a crucial role in calcification by promoting osteoblast differentiation in aortic valve tissues.
PMID: 31760051 [PubMed - as supplied by publisher]

Source: The Annals of Thoracic Surgery - November 20, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Sakaue T, Hamaguchi M, Aono J, Nakashiro KI, Shikata F, Kawakami N, Oshima Y, Kurata M, Nanba D, Masumoto J, Yamaguchi O, Higashiyama S, Izutani H Tags: Ann Thorac Surg Source Type: research