Doctors warn of ‘feather duvet lung’
Patients should be alert for respiratory problems on switching to feather bedding Related items fromOnMedica Cars should be banned from around schools More non-smokers dying from lung cancer Lung cancer incidence and mortality varies by cigarette type TB could be cured by four months ’ treatment in many patients Solid fuel cooking linked to higher respiratory death rate
This article presents a unique 3D biocompatible Aluminum-based quantum structure (QS) for in vitro cancer detection using Surface Enhanced Raman Scattering (SERS). The Al-based QSs fabricated using ultrashort pulsed laser are of two distinct surface characters, wrinkled and smooth spherical. The limit of detection for chemical sensing of Crystal Violet and Rhodamine 6G by the Al-QS was driven up to single molecule sensing (femtomolar concentration). Biological sensing of cysteine, a disease biomarker and carcinoembryonic antigen (CEA), a cancer biomarker was also tested by the Al-QS. The ability of in vitro cell detection ...
CONCLUSIONS Itraconazole altered the stemness characteristics of A549 and NCI-H460 human lung cancer cells by suppressing Wnt signaling but did not affect cell viability. PMID: 31833479 [PubMed - in process]
In their recently published article in the Journal, Latif and colleagues1 retrospectively demonstrated that patients undergoing resection of non –small cell lung cancer are at higher risk for recurrence and decreased longevity if they receive 2 or more units of blood in the perioperative period. In his correspondence addressing this article, Dr Baciewicz highlights several factors potentially associated both with increasing transfusion re quirements and with detriments in overall and recurrence-free survival that are potentially confounding.
In this study, we investigate, in vitro, whether miRNA-593-5p inhibits NSCLC cell proliferation. To clarify its specific mechanism of inhibition, we used bioinformatics to predict its target genes and identified PLK1. Luciferase reporter assay confirmed the binding of miR-593-5p to the PLK1 3’-UTR in a sequence-specific manner in NSCLC cells. Additionally, we also found through Western blot and quantitative RT-PCR that miR-593-5p down-regulates the expression of PLK1 protein. Finally, PLK1 overexpression was shown to disinhibit NSCLC cell proliferation. Taken together, this evidence suggests that miR-593-5p inhibits ...
ConclusionsOccult nodal disease was frequently identified in peripheral N1 stations (11-13) in patients with small (≤2 cm) clinical N0 NSCLC. Hilar lymphadenectomy is essential for accurate staging in the management of patients with small clinical N0 NSCLC.
Conclusion: MiR-7-5p suppresses NSCLC metastasis. Targeting miR-7-5p may contribute to the success of NSCLC therapy. PMID: 31832068 [PubMed - in process]
Publication date: Available online 13 December 2019Source: Journal of PhysiotherapyAuthor(s): Morten Quist
ConclusionThis may be achieved through adoption of stringent air pollution regulations and sustainable city planning. Increase in urban green infrastructures and improving road transportation will reduce PM2.5 levels in urban environment, thereby safeguarding human health from air pollution and improving citizens’ well-being.