Aedes aegypti Immune Response and Its Potential Impact on Dengue Virus Transmission

Viral Immunology, Ahead of Print.
Source: Viral Immunology - Category: Allergy & Immunology Authors: Source Type: research

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Authors: Devarasu N, Sudha GF Abstract A noninvasive investigation to ascertain the platelet (PLT) count was conducted on 44 hospitalized dengue hemorrhagic fever (DHF) subjects, male and female aged between 3 and 14 years using bioelectrical phase angle (BPhA). Among the 44 subjects, 30 subjects were confirmed to be non-structural protein-1 (NS1) positive at the time of admission, whose blood investigations such as hematocrit (HCT) level, PLT count, aspartate aminotransferase (AST) level and alanine aminotransferase (ALT) level were performed for the classification of risk as low-risk (LR) and high-risk (HR) DHF. ...
Source: Biomedizinische Technik/Biomedical Engineering - Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research
ela Korovou Climate change is known to affect Pacific Island nations in a variety of ways. One of them is by increasing the vulnerability of human health induced by various climate change impacts, which pose an additional burden to the already distressed health systems in the region. This paper explores the associations between climate change and human health on the one hand, and outlines some of the health care challenges posed by a changing climate on the other. In particular, it describes the links between climate variations and the emergence of climate-sensitive infectious diseases, such as the mosquito-borne disea...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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Source: International Journal of Environmental Health Research - Category: Environmental Health Authors: Source Type: research
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Annelies Wilder-Smith, Stefan Flasche, Peter G Smith
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Basu Dev Pandey, Anthony Costello
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Mohammed A Mamun, Jannatul Mawa Misti, Mark D Griffiths, David Gozal
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Thais Helena dos Santos, Jose L San Martin, Luis G Castellanos, Marcos A Espinal
Source: The Lancet - Category: General Medicine Source Type: research
This study aimed to compare the replicative fitness of the four dengue virus serotypes and understand the association between the serotypes, their in vitro infection ability, and their replication in target cells. We used three isolates of each DENV serotype to infect Huh-7 cells at an MOI of 0.5. The percentage of infected cells was evaluated by flow cytometry, cell viability was evaluated by MTT assay, and the pathogenicity index was calculated as a ratio of both parameters. The replicative fitness was measured by the number of viral genome copies produced using quantitative PCR and the production of infectious viral pro...
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research
Conclusionsthe applicability of the developed methodology to predict the dynamic behaviour of deaths caused by traffic injuries in Colombia for 2010 by means of a probabilistic random walk was confirmed with a good precision, suggesting that this methodology could be useful to verify the efficacy of national road safety strategies implemented to reduce mortality rates.
Source: Accident Analysis and Prevention - Category: Accident Prevention Source Type: research
Publication date: Available online 12 December 2019Source: BiologicalsAuthor(s): Hebleen Brenes, Gilbert D. Loría, Bruno LomonteAbstractSecreted phospholipase A2 (sPLA2) molecules are small, calcium-dependent enzymes involved in many biological processes. Viperid venoms possess gIIA sPLA2s and sPLA2-like proteins, both having homology to human gIIA sPLA2, an innate immunity enzyme. We evaluated the antiviral action of Mt–I (catalytically-active sPLA2) and Mt-II (catalytically-inactive variant) isolated from the venom of Bothrops asper, against a diverse group of viruses. Yellow Fever and Dengue (enveloped) vir...
Source: Biologicals - Category: Biology Source Type: research
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