Companion Diagnostics to Identify Biomarkers of Response to Anticancer Drugs Targeting the Proteome

Publication date: 11 November 2019Source: Cancer Cell, Volume 36, Issue 5Author(s): Anthony M. Joshua, Ian F. TannockIn this issue of Cancer Cell, Pillarsetty and colleagues radiolabel the potential anticancer drug PU-H71 and use it with PET imaging to quantify the epichaperome protein complex in tumors and its inhibition by the drug. They thereby develop a companion diagnostic paradigm of probe-drug pairing to explore therapeutic potential.
Source: Cancer Cell - Category: Cancer & Oncology Source Type: research