Sustained cancer clinical trial activity in a French hospital during the first wave of the COVID-19 pandemic
Publication date: Available online 18 June 2021Source: Cancer CellAuthor(s): Arnaud Bayle, Capucine Baldini, Patricia Martin-Romano, Jean-Marie Michot, Stéphane Champiat, Rastilav Bahleda, Anas Gazzah, Aurélien Marabelle, Loic Verlingue, Arthur Geraud, Daphné Morel, Stefan Michiels, Antoine Hollebecque, Laurence Albiges, Benjamin Besse, Jean-Charles Soria, Christophe Massard, Fabrice Barlesi, Sophie Postel-Vinay (Source: Cancer Cell)
Source: Cancer Cell - June 19, 2021 Category: Cancer & Oncology Source Type: research

Immunogenicity of SARS-CoV-2 messenger RNA Vaccines in Patients with Cancer
Publication date: Available online 18 June 2021Source: Cancer CellAuthor(s): Alfredo Addeo, Pankil K. Shah, Natacha Bordry, Robert D. Hudson, Brenna Albracht, Mariagrazia Di Marco, Virginia Kaklamani, Pierre-Yves Dietrich, Barbara S. Taylor, Pierre-Francois Simand, Darpan Patel, Jing Wang, Intidhar Labidi-galy, Sarah Fertani, Robin J. Leach, Jose Sandoval, Ruben Mesa, Kate Lathrop, Nicolas Mach, Dimpy P. Shah (Source: Cancer Cell)
Source: Cancer Cell - June 19, 2021 Category: Cancer & Oncology Source Type: research

Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial
Publication date: Available online 17 June 2021Source: Cancer CellAuthor(s): Lajos Pusztai, Christina Yau, Denise M. Wolf, Hyo S. Han, Lili Du, Anne M. Wallace, Erica String-Reasor, Judy C. Boughey, A. Jo Chien, Anthony D. Elias, Heather Beckwith, Rita Nanda, Kathy S. Albain, Amy S. Clark, Kathleen Kemmer, Kevin Kalinsky, Claudine Isaacs, Alexandra Thomas, Rebecca Shatsky, Theresa L. Helsten (Source: Cancer Cell)
Source: Cancer Cell - June 18, 2021 Category: Cancer & Oncology Source Type: research

Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma
Publication date: Available online 17 June 2021Source: Cancer CellAuthor(s): Oskar Marin-Bejar, Aljosja Rogiers, Michael Dewaele, Julia Femel, Panagiotis Karras, Joanna Pozniak, Greet Bervoets, Nina Van Raemdonck, Dennis Pedri, Toon Swings, Jonas Demeulemeester, Sara Vander Borght, Stefan Lehnert, Francesca Bosisio, Joost J. van den Oord, Isabelle Vanden Bempt, Diether Lambrechts, Thierry Voet, Oliver Bechter, Helen Rizos (Source: Cancer Cell)
Source: Cancer Cell - June 18, 2021 Category: Cancer & Oncology Source Type: research

Seroconversion rates following COVID-19 vaccination among patients with cancer
Publication date: Available online 5 June 2021Source: Cancer CellAuthor(s): Astha Thakkar, Jesus D. Gonzalez-Lugo, Niyati Goradia, Radhika Gali, Lauren C. Shapiro, Kith Pradhan, Shafia Rahman, So Yeon Kim, Brian Ko, R. Alejandro Sica, Noah Kornblum, Lizamarie Bachier-Rodriguez, Margaret McCort, Sanjay Goel, Roman Perez-Soler, Stuart Packer, Joseph Sparano, Benjamin Gartrell, Della Makower, Yitz D. Goldstein (Source: Cancer Cell)
Source: Cancer Cell - June 16, 2021 Category: Cancer & Oncology Source Type: research

Molecular classification and diagnostics of upper urinary tract urothelial carcinoma
Publication date: 14 June 2021Source: Cancer Cell, Volume 39, Issue 6Author(s): Yoichi Fujii, Yusuke Sato, Hiromichi Suzuki, Nobuyuki Kakiuchi, Tetsuichi Yoshizato, Andrew T. Lenis, Shigekatsu Maekawa, Akira Yokoyama, Yasuhide Takeuchi, Yoshikage Inoue, Yotaro Ochi, Yusuke Shiozawa, Kosuke Aoki, Kenichi Yoshida, Keisuke Kataoka, Masahiro M. Nakagawa, Yasuhito Nannya, Hideki Makishima, Jimpei Miyakawa, Taketo Kawai (Source: Cancer Cell)
Source: Cancer Cell - June 15, 2021 Category: Cancer & Oncology Source Type: research

STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
Publication date: 14 June 2021Source: Cancer Cell, Volume 39, Issue 6Author(s): Biniam Adane, Gabriela Alexe, Bo Kyung A. Seong, Diana Lu, Elizabeth E. Hwang, Denes Hnisz, Caleb A. Lareau, Linda Ross, Shan Lin, Filemon S. Dela Cruz, Melissa Richardson, Abraham S. Weintraub, Sarah Wang, Amanda Balboni Iniguez, Neekesh V. Dharia, Amy Saur Conway, Amanda L. Robichaud, Benjamin Tanenbaum, John M. Krill-Burger, Francisca Vazquez (Source: Cancer Cell)
Source: Cancer Cell - June 15, 2021 Category: Cancer & Oncology Source Type: research

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
Publication date: 14 June 2021Source: Cancer Cell, Volume 39, Issue 6Author(s): Silvia Affo, Ajay Nair, Francesco Brundu, Aashreya Ravichandra, Sonakshi Bhattacharjee, Michitaka Matsuda, LiKang Chin, Aveline Filliol, Wen Wen, Xinhua Song, Aubrianna Decker, Jeremy Worley, Jorge Matias Caviglia, Lexing Yu, Deqi Yin, Yoshinobu Saito, Thomas Savage, Rebecca G. Wells, Matthias Mack, Lars Zender (Source: Cancer Cell)
Source: Cancer Cell - June 15, 2021 Category: Cancer & Oncology Source Type: research

Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity
Publication date: Available online 10 June 2021Source: Cancer CellAuthor(s): Andrew Chow, Sara Schad, Michael D. Green, Matthew D. Hellmann, Viola Allaj, Nicholas Ceglia, Giulia Zago, Nisargbhai S. Shah, Sai Kiran Sharma, Marissa Mattar, Joseph Chan, Hira Rizvi, Hong Zhong, Cailian Liu, Yonina Bykov, Dmitriy Zamarin, Hongyu Shi, Sadna Budhu, Corrin Wohlhieter, Fathema Uddin (Source: Cancer Cell)
Source: Cancer Cell - June 11, 2021 Category: Cancer & Oncology Source Type: research

Developing and validating model systems for immuno-oncology
Publication date: Available online 10 June 2021Source: Cancer CellAuthor(s): Claire E. McCarthy, Nastaran Zahir, Mariam Eljanne, Elad Sharon, Emile E. Voest, Karolina Palucka (Source: Cancer Cell)
Source: Cancer Cell - June 11, 2021 Category: Cancer & Oncology Source Type: research

Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states
Publication date: Available online 10 June 2021Source: Cancer CellAuthor(s): Kamen P. Simeonov, China N. Byrns, Megan L. Clark, Robert J. Norgard, Beth Martin, Ben Z. Stanger, Jay Shendure, Aaron McKenna, Christopher J. Lengner (Source: Cancer Cell)
Source: Cancer Cell - June 11, 2021 Category: Cancer & Oncology Source Type: research

Seroconversion rates following COVID-19 vaccination amongst patients with cancer
Publication date: Available online 5 June 2021Source: Cancer CellAuthor(s): Astha Thakkar, Jesus D. Gonzalez-Lugo, Niyati Goradia, Radhika Gali, Lauren C. Shapiro, Kith Pradhan, Shafia Rahman, So Yeon Kim, Brian Ko, R. Alejandro Sica, Noah Kornblum, Lizamarie Bachier-Rodriguez, Margaret McCort, Sanjay Goel, Roman Perez-Soler, Stuart Packer, Joseph Sparano, Benjamin Gartrell, Della Makower, Yitz D. Goldstein (Source: Cancer Cell)
Source: Cancer Cell - June 6, 2021 Category: Cancer & Oncology Source Type: research

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
Publication date: Available online 3 June 2021Source: Cancer CellAuthor(s): Toshiro Hara, Rony Chanoch-Myers, Nathan D. Mathewson, Chad Myskiw, Lyla Atta, Lillian Bussema, Stephen W. Eichhorn, Alissa C. Greenwald, Gabriela S. Kinker, Christopher Rodman, L. Nicolas Gonzalez Castro, Hiroaki Wakimoto, Orit Rozenblatt-Rosen, Xiaowei Zhuang, Jean Fan, Tony Hunter, Inder M. Verma, Kai W. Wucherpfennig, Aviv Regev, Mario L. Suvà (Source: Cancer Cell)
Source: Cancer Cell - June 5, 2021 Category: Cancer & Oncology Source Type: research

Macrophage-tumor cell intertwine drives the transition into a mesenchymal-like cellular state of glioblastoma
Publication date: Available online 3 June 2021Source: Cancer CellAuthor(s): Zhihong Chen, Dolores Hambardzumyan (Source: Cancer Cell)
Source: Cancer Cell - June 5, 2021 Category: Cancer & Oncology Source Type: research

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation
Publication date: Available online 27 May 2021Source: Cancer CellAuthor(s): Yuanming Cheng, Wei Xie, Brian F. Pickering, Karen L. Chu, Angela M. Savino, Xuejing Yang, Hanzhi Luo, Diu TT. Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas M. Rohwetter, Dinshaw J. Patel, Samie R. Jaffrey, Michael G. Kharas (Source: Cancer Cell)
Source: Cancer Cell - May 28, 2021 Category: Cancer & Oncology Source Type: research

Conserved pan-cancer microenvironment subtypes predict response to immunotherapy
Publication date: Available online 20 May 2021Source: Cancer CellAuthor(s): Alexander Bagaev, Nikita Kotlov, Krystle Nomie, Viktor Svekolkin, Azamat Gafurov, Olga Isaeva, Nikita Osokin, Ivan Kozlov, Felix Frenkel, Olga Gancharova, Nava Almog, Maria Tsiper, Ravshan Ataullakhanov, Nathan Fowler (Source: Cancer Cell)
Source: Cancer Cell - May 21, 2021 Category: Cancer & Oncology Source Type: research

Precision oncology: Directing genomics and pharmacogenomics toward reducing cancer inequities
Publication date: Available online 20 May 2021Source: Cancer CellAuthor(s): Loren Saulsberry, Olufunmilayo I. Olopade (Source: Cancer Cell)
Source: Cancer Cell - May 21, 2021 Category: Cancer & Oncology Source Type: research

The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth
Publication date: Available online 20 May 2021Source: Cancer CellAuthor(s): Lihui Dong, Chuanyuan Chen, Yawei Zhang, Peijin Guo, Zhenghang Wang, Jian Li, Yi Liu, Jun Liu, Renbao Chang, Yilin Li, Guanghao Liang, Weiyi Lai, Mengxue Sun, Urszula Dougherty, Marc B. Bissonnette, Hailin Wang, Lin Shen, Meng Michelle Xu, Dali Han (Source: Cancer Cell)
Source: Cancer Cell - May 21, 2021 Category: Cancer & Oncology Source Type: research

A tumor “personality” test to guide therapeutic decision making
Publication date: Available online 20 May 2021Source: Cancer CellAuthor(s): Kathleen E. Houlahan, Christina Curtis (Source: Cancer Cell)
Source: Cancer Cell - May 21, 2021 Category: Cancer & Oncology Source Type: research

Interleukin-1 in tumor progression, therapy, and prevention
Publication date: Available online 13 May 2021Source: Cancer CellAuthor(s): Cecilia Garlanda, Alberto Mantovani (Source: Cancer Cell)
Source: Cancer Cell - May 14, 2021 Category: Cancer & Oncology Source Type: research

Translating inspiration from COVID-19 vaccine trials to innovations in clinical cancer research
Publication date: Available online 7 May 2021Source: Cancer CellAuthor(s): Noura J. Choudhury, Gregory J. Riely, Paul J. Sabbatini, Matthew D. Hellmann (Source: Cancer Cell)
Source: Cancer Cell - May 8, 2021 Category: Cancer & Oncology Source Type: research

Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer
Publication date: Available online 6 May 2021Source: Cancer CellAuthor(s): Milena Hornburg, Mélanie Desbois, Shan Lu, Yinghui Guan, Amy A. Lo, Susan Kaufman, Ashley Elrod, Alina Lotstein, Teresa M. DesRochers, Jose L. Munoz-Rodriguez, Xingwei Wang, Jennifer Giltnane, Oleg Mayba, Shannon J. Turley, Richard Bourgon, Anneleen Daemen, Yulei Wang (Source: Cancer Cell)
Source: Cancer Cell - May 7, 2021 Category: Cancer & Oncology Source Type: research

Progress and potential: the Cancer Moonshot
Publication date: Available online 6 May 2021Source: Cancer CellAuthor(s): Norman E. Sharpless, Dinah S. Singer (Source: Cancer Cell)
Source: Cancer Cell - May 7, 2021 Category: Cancer & Oncology Source Type: research

Seeing the forest for the trees—single-cell atlases link CD8+ T cells and macrophages to disease progression and treatment response in kidney cancer
Publication date: Available online 15 April 2021Source: Cancer CellAuthor(s): Mei Yee Koh, Nicolas Sayegh, Neeraj Agarwal (Source: Cancer Cell)
Source: Cancer Cell - May 4, 2021 Category: Cancer & Oncology Source Type: research

Evaluation of TMB as a predictive biomarker in patients with solid cancers treated with anti-PD-1/CTLA-4 combination immunotherapy
Publication date: Available online 29 April 2021Source: Cancer CellAuthor(s): Oliver Klein, Damien Kee, Ben Markman, Matteo S. Carlino, Craig Underhill, Jodie Palmer, Daniel Power, Jonathan Cebon, Andreas Behren (Source: Cancer Cell)
Source: Cancer Cell - May 1, 2021 Category: Cancer & Oncology Source Type: research

Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla
Publication date: Available online 29 April 2021Source: Cancer CellAuthor(s): Polina Kameneva, Artem V.Artemov, Maria Eleni Kastriti, Erik Sundström, Peter V. Kharchenko, Igor Adameyko (Source: Cancer Cell)
Source: Cancer Cell - May 1, 2021 Category: Cancer & Oncology Source Type: research

José Baselga (1959–2021)
Publication date: Available online 29 April 2021Source: Cancer CellAuthor(s): Pau Castel, Eneda Toska, Neil Vasan, Emiliano Cocco, Maurizio Scaltriti (Source: Cancer Cell)
Source: Cancer Cell - May 1, 2021 Category: Cancer & Oncology Source Type: research

STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma
Publication date: Available online 29 April 2021Source: Cancer CellAuthor(s): Didier Surdez, Sakina Zaidi, Sandrine Grossetête, Karine Laud-Duval, Anna Sole Ferre, Lieke Mous, Thomas Vourc'h, Franck Tirode, Gaelle Pierron, Virginie Raynal, Sylvain Baulande, Erika Brunet, Véronique Hill, Olivier Delattre (Source: Cancer Cell)
Source: Cancer Cell - May 1, 2021 Category: Cancer & Oncology Source Type: research

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
Publication date: Available online 29 April 2021Source: Cancer CellAuthor(s): Silvia Affo, Ajay Nair, Francesco Brundu, Aashreya Ravichandra, Sonakshi Bhattacharjee, Michitaka Matsuda, LiKang Chin, Aveline Filliol, Wen Wen, Xinhua Song, Aubrianna Decker, Jeremy Worley, Jorge Matias Caviglia, Lexing Yu, Deqi Yin, Yoshinobu Saito, Thomas Savage, Rebecca G. Wells, Matthias Mack, Lars Zender (Source: Cancer Cell)
Source: Cancer Cell - May 1, 2021 Category: Cancer & Oncology Source Type: research

Artificial intelligence for clinical oncology
Publication date: Available online 29 April 2021Source: Cancer CellAuthor(s): Benjamin H. Kann, Ahmed Hosny, Hugo J.W.L. Aerts (Source: Cancer Cell)
Source: Cancer Cell - May 1, 2021 Category: Cancer & Oncology Source Type: research

Targeting cell-cycle machinery in cancer
Publication date: Available online 22 April 2021Source: Cancer CellAuthor(s): Jan M. Suski, Marcin Braun, Vladislav Strmiska, Piotr Sicinski (Source: Cancer Cell)
Source: Cancer Cell - April 23, 2021 Category: Cancer & Oncology Source Type: research

Bacteria break barrier to promote metastasis
Publication date: Available online 22 April 2021Source: Cancer CellAuthor(s): Yoshitaka Murota, Christian Jobin (Source: Cancer Cell)
Source: Cancer Cell - April 23, 2021 Category: Cancer & Oncology Source Type: research

Seeing the forest for the trees—single-cell atlases link CD8+T cells and macrophages to disease progression and treatment response in kidney cancer
Publication date: Available online 15 April 2021Source: Cancer CellAuthor(s): Mei Yee Koh, Nicolas Sayegh, Neeraj Agarwal (Source: Cancer Cell)
Source: Cancer Cell - April 16, 2021 Category: Cancer & Oncology Source Type: research

Care without a compass: including patients with cancer in COVID-19 studies
Publication date: Available online 15 April 2021Source: Cancer CellAuthor(s): Christopher R. Friese, Toni K. Choueiri, Narjust Duma, Dimitrios Farmakiotis, Petros Grivas, Brian I. Rini, Dimpy P. Shah, Michael A. Thompson, Steven A. Pergam, Sanjay Mishra, Jeremy L. Warner (Source: Cancer Cell)
Source: Cancer Cell - April 16, 2021 Category: Cancer & Oncology Source Type: research

Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy
Publication date: Available online 15 April 2021Source: Cancer CellAuthor(s): Chirag Krishna, Renzo G. DiNatale, Fengshen Kuo, Raghvendra M. Srivastava, Lynda Vuong, Diego Chowell, Sounak Gupta, Chad Vanderbilt, Tanaya A. Purohit, Ming Liu, Emily Kansler, Briana G. Nixon, Ying-Bei Chen, Vladimir Makarov, Kyle A. Blum, Kyrollis Attalla, Stanley Weng, Michael L. Salmans, Mahdi Golkaram, Li Liu (Source: Cancer Cell)
Source: Cancer Cell - April 16, 2021 Category: Cancer & Oncology Source Type: research

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress
Publication date: 12 April 2021Source: Cancer Cell, Volume 39, Issue 4Author(s): Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli, Kelli M. Wilson, Yang Zhang, Erin Beck, Linda Sciuto, Samantha Nichols, Brian Elenbaas, Janusz Puc, Heike Dahmen, Astrid Zimmermann, Jillian Varonin, Christopher W. Schultz, Sehyun Kim, Hirity Shimellis, Parth Desai (Source: Cancer Cell)
Source: Cancer Cell - April 13, 2021 Category: Cancer & Oncology Source Type: research

Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription
Publication date: Available online 8 April 2021Source: Cancer CellAuthor(s): Yanfen Zhu, Amit D. Gujar, Chee-Hong Wong, Harianto Tjong, Chew Yee Ngan, Liang Gong, Yi-An Chen, Hoon Kim, Jihe Liu, Meihong Li, Adam Mil-Homens, Rahul Maurya, Chris Kuhlberg, Fanyue Sun, Eunhee Yi, Ana C. deCarvalho, Yijun Ruan, Roel G.W. Verhaak, Chia-Lin Wei (Source: Cancer Cell)
Source: Cancer Cell - April 10, 2021 Category: Cancer & Oncology Source Type: research

Redirecting macrophage function to sustain their “defender” antitumor activity
Publication date: Available online 1 April 2021Source: Cancer CellAuthor(s): Stephanie L. Tzetzo, Scott I. Abrams (Source: Cancer Cell)
Source: Cancer Cell - April 3, 2021 Category: Cancer & Oncology Source Type: research

Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver
Publication date: Available online 1 April 2021Source: Cancer CellAuthor(s): Alice Bertocchi, Sara Carloni, Paola Simona Ravenda, Giovanni Bertalot, Ilaria Spadoni, Antonino Lo Cascio, Sara Gandini, Michela Lizier, Daniele Braga, Francesco Asnicar, Nicola Segata, Chris Klaver, Paola Brescia, Elio Rossi, Achille Anselmo, Silvia Guglietta, Annalisa Maroli, Paola Spaggiari, Noelia Tarazona, Andres Cervantes (Source: Cancer Cell)
Source: Cancer Cell - April 3, 2021 Category: Cancer & Oncology Source Type: research

More reliable breast cancer risk assessment for every woman
Publication date: Available online 18 March 2021Source: Cancer CellAuthor(s): Han Liang (Source: Cancer Cell)
Source: Cancer Cell - March 31, 2021 Category: Cancer & Oncology Source Type: research

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
Publication date: Available online 18 March 2021Source: Cancer CellAuthor(s): Hua Su, Fei Yang, Rao Fu, Xin Li, Randall French, Evangeline Mose, Xiaohong Pu, Brittney Trinh, Avi Kumar, Junlai Liu, Laura Antonucci, Jelena Todoric, Yuan Liu, Yinling Hu, Maria T. Diaz-Meco, Jorge Moscat, Christian M. Metallo, Andrew M. Lowy, Beicheng Sun, Michael Karin (Source: Cancer Cell)
Source: Cancer Cell - March 20, 2021 Category: Cancer & Oncology Source Type: research

Size matters: toward reliable breast cancer risk assessment for every woman
Publication date: Available online 18 March 2021Source: Cancer CellAuthor(s): Han Liang (Source: Cancer Cell)
Source: Cancer Cell - March 20, 2021 Category: Cancer & Oncology Source Type: research

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma
Publication date: Available online 11 March 2021Source: Cancer CellAuthor(s): Kevin Bi, Meng Xiao He, Ziad Bakouny, Abhay Kanodia, Sara Napolitano, Jingyi Wu, Grace Grimaldi, David A. Braun, Michael S. Cuoco, Angie Mayorga, Laura DelloStritto, Gabrielle Bouchard, John Steinharter, Alok K. Tewari, Natalie I. Vokes, Erin Shannon, Maxine Sun, Jihye Park, Steven L. Chang, Bradley A. McGregor (Source: Cancer Cell)
Source: Cancer Cell - March 13, 2021 Category: Cancer & Oncology Source Type: research

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma
Publication date: Available online 11 March 2021Source: Cancer CellAuthor(s): David A. Braun, Kelly Street, Kelly P. Burke, David L. Cookmeyer, Thomas Denize, Christina B. Pedersen, Satyen H. Gohil, Nicholas Schindler, Lucas Pomerance, Laure Hirsch, Ziad Bakouny, Yue Hou, Juliet Forman, Teddy Huang, Shuqiang Li, Ang Cui, Derin B. Keskin, John Steinharter, Gabrielle Bouchard, Maxine Sun (Source: Cancer Cell)
Source: Cancer Cell - March 13, 2021 Category: Cancer & Oncology Source Type: research

Pancreatic cancer is suppressed by fibroblast-derived collagen I
Publication date: Available online 11 March 2021Source: Cancer CellAuthor(s): Chris D. Madsen (Source: Cancer Cell)
Source: Cancer Cell - March 13, 2021 Category: Cancer & Oncology Source Type: research

Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression
Publication date: 8 March 2021Source: Cancer Cell, Volume 39, Issue 3Author(s): Taoyong Chen, Mingjin Yang, Zhou Yu, Songqing Tang, Chen Wang, Xuhui Zhu, Jun Guo, Nan Li, Weiping Zhang, Jin Hou, Haibo Liu, Chaofeng Han, Qiuyan Liu, Yan Gu, Cheng Qian, Tao Wan, Long Cui, Minghua Zhu, Weiqiang Zheng, Xuetao Cao (Source: Cancer Cell)
Source: Cancer Cell - March 9, 2021 Category: Cancer & Oncology Source Type: research

A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation
Publication date: 8 March 2021Source: Cancer Cell, Volume 39, Issue 3Author(s): Gregory Lazarian, Shanye Yin, Elisa ten Hacken, Tomasz Sewastianik, Mohamed Uduman, Alba Font-Tello, Satyen H. Gohil, Shuqiang Li, Ekaterina Kim, Heather Joyal, Leah Billington, Elizabeth Witten, Mei Zheng, Teddy Huang, Mariano Severgnini, Valerie Lefebvre, Laura Z. Rassenti, Catherine Gutierrez, Katia Georgopoulos, Christopher J. Ott (Source: Cancer Cell)
Source: Cancer Cell - March 9, 2021 Category: Cancer & Oncology Source Type: research

A gene expression signature associated with ‘‘K-Ras addiction’’ reveals regulators of EMT and tumor cell survival
Publication date: 8 March 2021Source: Cancer Cell, Volume 39, Issue 3Author(s): Anurag Singh, Patricia Greninger, Daniel Rhodes, Louise Koopman, Sheila Violette, Nabeel Bardeesy, Jeff Settleman (Source: Cancer Cell)
Source: Cancer Cell - March 9, 2021 Category: Cancer & Oncology Source Type: research

Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
Publication date: Available online 4 March 2021Source: Cancer CellAuthor(s): Yang Chen, Jiha Kim, Sujuan Yang, Huamin Wang, Chang-Jiun Wu, Hikaru Sugimoto, Valerie S. LeBleu, Raghu Kalluri (Source: Cancer Cell)
Source: Cancer Cell - March 5, 2021 Category: Cancer & Oncology Source Type: research

MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
Publication date: Available online 4 March 2021Source: Cancer CellAuthor(s): Koki Ueda, Rajni Kumari, Emily Schwenger, Justin C. Wheat, Oliver Bohorquez, Swathi-Rao Narayanagari, Samuel J. Taylor, Luis A. Carvajal, Kith Pradhan, Boris Bartholdy, Tihomira I. Todorova, Hiroki Goto, Daqian Sun, Jiahao Chen, Jidong Shan, Yinghui Song, Cristina Montagna, Shunbin Xiong, Guillermina Lozano, Andrea Pellagatti (Source: Cancer Cell)
Source: Cancer Cell - March 5, 2021 Category: Cancer & Oncology Source Type: research