Epidemiology and clinical course of hepatitis A in Cantabria before and after the epidemic outbreak of June 2016

ConclusionsOur results reaffirm the high clinical and epidemiological impact of the epidemic outbreak in Cantabria and emphasises the need for optimising the current prevention measures against hepatitis A.ResumenAntecedentes y objetivos: Desde junio de 2016 se han producido brotes de hepatitis A en diversos países europeos, afectando principalmente a hombres que tienen sexo con hombres (HSH). El objetivo del presente trabajo fue valorar su impacto clínico y epidemiológico en Cantabria.Materiales y métodosSe recogieron retrospectivamente todos los casos de hepatitis A diagnosticados en Cantabria entre enero de 2013 y septiembre de 2018. Se compararon dos periodos (enero 2013-mayo 2016 y junio 2016-septiembre 2018).ResultadosSe diagnosticaron un total de 156 casos, objetivándose un aumento de la incidencia a partir de octubre de 2016. Con respecto al periodo 2013-2016, se observó una mayor proporción de varones (50,0 vs. 84,5%; p = 0,012) con una predominancia de la orientación sexual homosexual (80,6%) y una mayor frecuencia de transmisión sexual (0 vs. 48,3%; p = 0,061) en los pacientes del periodo 2016-2018. Desde el punto de vista clínico destacó que todos los casos de hepatitis grave ocurrieron en este último periodo.ConclusionesNuestros resultados reafirman el elevado impacto clínico y epidemiológico del brote epidémico en Cantabria y ponen de reli...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research

Related Links:

Conclusions: A higher seroprevalence of HEV as compared to HAV together with a co-infection rate of 2.07% mandates screening for HEV in all suspected cases of acute hepatitis, particularly pregnant women in whom the outcomes of HEV infection are poor. Health and civic authorities should make necessary efforts to counter epidemic or outbreak situations, thus reducing morbidity, mortality and economic burden.
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
Authors: Kang SH, Kim MY, Baik SK Abstract Until 1995, the incidence of symptomatic acute hepatitis A was minimal and there were no cases of national outbreak in Korea. However, there was a nationwide outbreak of hepatitis A that peaked in 2009. In 2019, a total of 10,083 cases of acute hepatitis A were reported for seven months of the year according to the Korea Center for Disease Control and Prevention. This may be attributed to the proportion of susceptible subjects in the Korean population, as about 10 years have passed since herd immunity was induced by the epidemic occurring during the late 2000s. Recent stud...
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
This study focused on the molecular characterization and phylogenetic analysis of the EVs and HAVs identified in 33 sewage samples collected every 15  days at the influent of a wastewater treatment plant located in Northern Italy from March to October 2016. According to the results of the molecular characterization, the most frequently identified viruses were Echovirus 6 (E-6), E-11 and HAV-IA. The phylogenetic analyses indicated the rapid genet ic evolution of E-6 and E-1; noteworthy, most E-11 strains clustered with a strain isolated from a clinical sample collected in the same geographical area over the same period...
Source: Food and Environmental Virology - Category: Virology Source Type: research
Publication date: Available online 13 June 2019Source: EpidemicsAuthor(s): Giorgio GuzzettaAbstractA major outbreak of Hepatitis A Virus (HAV) has swept through Europe between mid-2016 and 2017, mainly within the community of men who have sex with men (MSM). Over the same period, about 1,000 outbreak-related cases of acute Hepatitis A (AHA) were recorded in Lazio region, Italy.We calibrated a Bayesian model to reconstruct likely transmission events within all 44 households where multiple infections were recorded, representing a total of 103 cases from the HAV outbreak in Lazio. Based on information on the observed times of...
Source: Epidemics - Category: Epidemiology Source Type: research
Conclusions Apart West Nile virus (78), thousands of congenital microcephaly cases, fetal brain tissue damage and neurological syndromes have been associated with ZIKV infection. Unfortunately, the epidemics of this mosquito born, and a relative stable virus is on a rise. Although congenital microcephaly is a rare disorder however, due to lack of standardized diagnostic test facilities, the incidence in the geographically widespread ZIKV epidemic regions is higher. Animals studies showed that ZIKV is a neurotropic virus. It directly targets the developing embryonic brain cells by inducing apoptosis, cell-cycle arrest, and...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Abstract Nearly 1 million people become infected every day with any of the four major curable sexually transmitted infections (STIs), namely trichomoniasis, chlamydia, gonorrhea, and syphilis. Despite huge global incidence, STIs remain as neglected diseases. The success of antiretrovirals for halting progression to AIDS in HIV-infected individuals and for stopping HIV transmission to uninfected contacts, either as pre- or post-exposure -prophylaxis, has to lead to increased risky sexual behaviors through risk compensation. Recent epidemics and outbreaks of STIs among men having sex with men reflect the global loss...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
You can learn a lot about a person’s medical concerns by looking at the health topics they’ve searched for online. It’s fascinating (and a bit creepy) to take a peek at what others are searching — and to compare what you find to what sends you online. I’ve posted before about how the health issues people report worrying about the most differ from those that are most common, deadly, or have the biggest impact on quality of life. There’s overlap, of course, but certain important conditions (such as lung disease, the third leading cause of death in 2015) did not make the top 10 list of heal...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Source Type: blogs
Background: Several EU countries reported large increases in hepatitis A cases in 2017 compared to previous years. From January to May 110 cases were reported in Poland, mainly in MSM population, what is 10 times more than in the corresponding periods of 2014 – 2016. HIV-positive patients have low adherence to recommended HAV vaccination. Due to local epidemic situation Hepatitis A vaccine is available against payment (40$) in HIV Clinic in Warsaw from May 2017.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: UMP. 359 Source Type: research
A San Diego County grand jury report faults local response to a recent hepatitis A epidemic and recommends improving lines of communication to prepare for future health emergencies
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
San Diego's mayor said he agrees with a county grand jury report that found lines of communication among authorities were lacking during the recent Hepatitis A epidemic
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
More News: Epidemics | Epidemiology | Hepatitis | Hepatitis A | Internal Medicine | Outbreaks | Spain Health | Study