Bone Defect Management with Vascularized Fibular Grafts in the Treatment of Grade III-IV Osteomyelitis.

CONCLUSIONS: The bone defect reconstruction with vascularized fibula grafts in severe bone infections is an effective option, but requires a well trained multidisciplinary team to manage the high rate of complications. Complications, in our series, were demonstrated to be significantly associated to patients defined as B-hosts according to Cierny-Mader's classification (P
Source: Handchirurgie Mikrochirurgie Plastische Chirurgie - Category: Cosmetic Surgery Tags: Handchir Mikrochir Plast Chir Source Type: research

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Source: British Journal of Neurosurgery - Category: Neurosurgery Authors: Source Type: research
This study aims to assess a treatment strategy that may enable the reduction of systemic antibiotic use for patients with orthopaedic infection. If this strategy is non-inferior, this will be to the advantage of patients and contribute to antimicrobial stewardship.Trial registrationClinicaltrials.gov,NCT03806166. Registered on 11 November 2019.
Source: Trials - Category: Research Source Type: clinical trials
Soft tissue reconstruction of chronic lower extremity wounds represents a challenging problem, especially when wounds are complicated by bone infection. Treatment consists of multi-disciplinary management with plastic and orthopaedic surgeons and the support of the infectious disease team. Surgery involves radical debridement and soft-tissue coverage preferably carried out at the same time, as well as appropriate antibiotics guided by the microbiology results from the bone specimen. Normal bone is highly resistant to infection with a low overall incidence of osteomyelitis [1], in the US osteomyelitis arises in 22 per 100,0...
Source: Injury - Category: Orthopaedics Authors: Source Type: research
DISCUSSION: The association of FG and NPWT is not known in the clinical practice. Except for the only one experimental study described by Kao et al.4, the theme was not addressed in the medical literature before. In this clinical case, the result obtained regarding the granulation tissue formation drew attention and prevented the use of more complex flaps such as the microsurgical ones. Accelerated granulation tissue formation was observed, filling an extensive and deep bone defect, even with infected bone and biomaterial. Low morbidity and no complications were observed with the use of FG associated with NPWT. When the gr...
Source: Acta Cirurgica Brasileira - Category: Surgery Authors: Tags: Acta Cir Bras Source Type: research
Authors: George E, Rajalakshmi A Abstract Melioidosis is an infectious disease caused by gram negative bacterium Burkholderia pseudomallei. It is a soil and water pathogen and transmitted to humans through inoculation or inhalation. This disease is considered endemic in India and largely remains under reported. The most common presentation is pneumonia and bacteraemia, which can present acutely and as septic shock. Chronic presentation include-abscess, septic arthritis, osteomyelitis. The major risk factors are diabetes, liver disease, renal disease, chronic lung disease. In this article 18 cases have been reviewed...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
We present a case report of Pott’s puffy tumor with frontal sinus and epidural abscess, and review the literature with proposal of terminology change to a more accurate description as Pott’s puffy “abscess”.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
CONCLUSIONS: The TIDOS project has focused research on four initiatives: (1) blast-related wound infection epidemiology and clinical management; (2) DoD-VA outcomes research; (3) Multidrug- Resistant and other Virulent Organisms Trauma Infections Initiative; and (4) Joint Trauma System clinical practice guidelines and antibiotic stewardship. There is a continuing need for longitudinal data platforms to support battlefield wound research and clinical practice guideline recommendation refinement, particularly to improve care for future conflicts. As such, maintaining a research platform, such as TIDOS, would negate the lengt...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
ConclusionOral bisphosphonates appear to provide prolonged symptom relief in patients with DSO compared to previous treatment strategies, however the exact regime and length of use is still unknown. The positive impact of bisphosphonates may provide a potential insight into the pathophysiology of DSO.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
Publication date: Available online 29 November 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Marieke M. van de Meent, Miranda J.M. Wetselaar-Glas, Marta Fiocco, Natasha M. Appelman-Dijkstra, J.P.Richard van MerkesteynSummaryNon-surgical therapy has proved to be effective in chronic diffuse sclerosing osteomyelitis (DSO) of the mandible in children. Therefore we aimed to investigate the effect of non-surgical therapy in adult DSO patients.We included consecutive patients with DSO who received non-surgical therapy in our center. They all received occlusal splint therapy, counselling about the disease, and/or ...
Source: Journal of Cranio Maxillofacial Surgery - Category: ENT & OMF Source Type: research
I congratulate the authors for presenting a minimally invasive approach to pubic symphyseal debridement with or without cystectomy in patients with urosymphyseal fistulas (USFs). Although a rare complication of prostate cancer radiotherapy treatment, USF and its associated osteomyelitis frequently result in debilitating pain, sepsis, decreased quality of life, and potentially increased mortality. The traditional treatment of this difficult problem has been to perform an open pubic bone debridement with either cystectomy and ileal conduit if the bladder is not salvageable, or to perform a USF closure with rectus muscle flap...
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
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