The Construction and Characterization of Mirror-imaged L-DNA i-Motif.

The Construction and Characterization of Mirror-imaged L-DNA i-Motif.
Chembiochem. 2019 Oct 28;:
Authors: Sun Y, Yang B, Hua Y, Dong Y, Ye J, Wang J, Xu L, Liu D
Abstract
The first thermal stable and pH-responsive tetraplex i-motif structure formed by L -DNA is presented. Although this L -type i-motif exhibits the same physiochemical properties as its D -isomer, its inverted chirality and good enzymatic resistance opens the way to the development of new DNA materials of pharmaceutical and biological interest.
PMID: 31659823 [PubMed - as supplied by publisher]

Source: Chembiochem - October 27, 2019 Category: Biochemistry Authors: Sun Y, Yang B, Hua Y, Dong Y, Ye J, Wang J, Xu L, Liu D Tags: Chembiochem Source Type: research