Angiopoietin-Like Protein 2 Is a Potent Hemangiogenic and Lymphangiogenic Factor in Corneal Inflammation [Cornea]

Conclusions.
Our findings demonstrated Angptl2 to be upregulated in corneal inflammation, and highlight that corneal hemangiogenesis and lymphangiogenesis may be driven by Angptk2 overexpression via macrophage infiltration and IL-1β expression. Angptl2 may be a novel therapeutic target for preventing blindness.

Source: Investigative Ophthalmology - June 26, 2013 Category: Opthalmology Authors: Toyono, T., Usui, T., Yokoo, S., Kimakura, M., Nakagawa, S., Yamagami, S., Miyata, K., Oike, Y., Amano, S. Tags: Cornea Source Type: research