Comparison of BEAMing and Droplet Digital PCR for Circulating Tumor DNA Analysis [Cancer Diagnostics]

CONCLUSIONS:
This large, clinically relevant comparison showed good agreement between BEAMing and ddPCR, suggesting sufficient reproducibility for clinical use. Much of the observed discordancy may be related to sampling effects, potentially explaining many of the differences in the currently available ctDNA literature.

Source: Clinical Chemistry - October 28, 2019 Category: Chemistry Authors: O'Leary, B., Hrebien, S., Beaney, M., Fribbens, C., Garcia-Murillas, I., Jiang, J., Li, Y., Huang Bartlett, C., Andre, F., Loibl, S., Loi, S., Cristofanilli, M., Turner, N. C. Tags: Cancer Diagnostics (since 2002) Source Type: research