Osteoprotegerin and Osteopontin Serum Levels are Associated with Vascular Function and Inflammation in Coronary Artery Disease Patients.

CONCLUSION: CAD patients have increased osteoprotegerin, osteopontin and IL-6 levels. Moreover, there is a consistent association between osteoprotegerin and osteopontin serum levels, vascular function and inflammation in CAD patients. These findings suggest another possible mechanism linking osteoprotegerin and osteopontin serum levels with CAD progression through arterial wall stiffening and inflammation.
PMID: 31642412 [PubMed - as supplied by publisher]

Source: Current Vascular Pharmacology - October 20, 2019 Category: Drugs & Pharmacology Authors: Maniatis K, Siasos G, Oikonomou E, Vavuranakis M, Zaromytidou M, Mourouzis K, Paraskevopoulos T, Charalambous G, Papavassiliou AG, Tousoulis D Tags: Curr Vasc Pharmacol Source Type: research