Body muscle-to-fat ratio gender-specific cut-off values for impaired insulin sensitivity in patients with treatment-na ïve type 2 diabetes mellitus

We examined BMFR gender-specific cut-off values for impaired insulin sensitivity in treatment-na ïve type 2 diabetes mellitus (T2DM) patients.MethodsSubjects included 101 untreated T2DM patients (male, 66; female, 35). We performed a hyperinsulinemic –euglycemic clamp examination to measure the steady-state glucose infusion rate (M value) as an indicator of whole-body insulin resistance. We defined theM value divided by the steady-state serum insulin value as theM/I value. We defined the existence of insulin resistance using anM/I ratio
Source: Endocrine - Category: Endocrinology Source Type: research

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Source: - Category: Research Source Type: clinical trials
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.9b04931
Source: Journal of Agricultural and Food Chemistry - Category: Food Science Authors: Source Type: research
Conclusion: The survival rate of dental implant placement by conventional and flapless techniques is similar. As few studies on flapless technique are available, therefore researchers in future should explore its advantages and disadvantages.
Source: Indian Journal of Dental Research - Category: Dentistry Authors: Source Type: research
Type 2 diabetes mellitus (T2DM) and associated ailments are leading economic burdens to society. Sodium glucose cotransporter-2 (SGLT2) inhibitors are recent antidiabetic medications with beneficial clinical efficacy. This meta-analysis was conducted to quantitatively pool the incremental net benefit of SGLT2 inhibitors in T2DM patients who failed metformin monotherapy.
Source: Value in Health - Category: International Medicine & Public Health Authors: Source Type: research
AbstractType 2 diabetes mellitus type 2 (T2DM) is an endocrine metabolic disorder, occurring worldwide due to aging, advancement in lifestyle by modernization. T2DM is characterized by higher levels of glucose in the blood due to unresponsive secretion of pancreatic insulin and insulin activity or altogether. T2DM, regarded as a powerful genetic susceptible disease that leads to high risk with insulin resistance and β‐cell dysfunction. To manage and overcome type 2 diabetes, physical activity, diet strategies, and other therapeutic medications along with usage of anti‐glycemic agents are developed and attempted ap...
Source: Biotechnology and Applied Biochemistry - Category: Biochemistry Authors: Tags: Mini ‐Review Source Type: research
We report a case of a 36-year-old woman with type 2 diabetes mellitus and a one-year of primary infertility. Following oral ovulation induction cycles and IUI, diagnosis of heterotopic cervical pregnancy was made by ultrasonography at 7.4 weeks of gestation. Laser ablation of the cervical pregnancy was performed achieving adequate homeostasis at the implantation site and preserving the intrauterine pregnancy. A healthy infant was delivered at 36 0/7 wks by cesarean-section.Laser ablation is a minimally invasive procedure that appears to lead to successful outcomes in treatment of heterotopic cervical pregnancy.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Controversies exist regarding the optimal blood pressure (BP) level that is safe and provides cardiovascular protection in patients with type 2 diabetes mellitus (T2DM) and coexistent coronary artery disease. ...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Review Source Type: research
AbstractBackgroundSingle anastomosis sleeve ileal (SASI) bypass is a newly introduced bariatric and metabolic procedure. The present multicenter study aimed to evaluate the efficacy of the SASI bypass in the treatment of patients with morbid obesity and the metabolic syndrome.MethodsThis is a retrospective, seven-country, multicenter study on patients with morbid obesity who underwent the SASI bypass. Data regarding patients ’ demographics, body mass index (BMI), percentage of total weight loss (%TWL), percentage of excess weight loss (%EWL), and improvement in comorbidities at 12 months postoperatively and postopera...
Source: Obesity Surgery - Category: Surgery Source Type: research
The objective of this study was 1) to assess the relationship between diagnosed DLP and cardiovascular disease in COPD patients and compare it with other known cardiovascular risk factors and 2) to determine the relationship between the different cardiovascular comorbidities and the severity groups according to the GOLD 2017 classification.MethodsA cross-sectional, observational study was performed in 454 outpatients with COPD during their follow up. We calculated the prevalence of each of the cardiovascular comorbidities and the probability of each of the cardiovascular risk factors to occur jointly with a vascular diseas...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research
The findings of recent clinical trials have shown that sodium-glucose co-transporter 2 (SGLT2) inhibitors produce effects beyond glucose lowering and have demonstrated beneficial cardiovascular effects that have been observed across a broad range of patients with type 2 diabetes mellitus. In particular, the cardiovascular benefit results largely from substantial and early effects of SGLT2 inhibition on cardiovascular death and hospitalization for heart failure. Recent cardiovascular outcomes trials (CVOTs) have also shown that relative risk reductions in cardiovascular outcomes were observed with SGLT2 inhibition both in p...
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
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