Combined therapy with platelet rich plasma and basic fibroblast growth factor in the early healing of rotator cuff tear in a rat model

Retears are a common complication after surgical repair of large and massive rotator cuff tears. Basic fibroblast growth factor (b-FGF) and platelet rich plasma (PRP) reportedly enhance the healing of rotator cuff tears. The purpose of this study was to evaluate the efficacy of PRP and b-FGF using a gelatin hydrogel sheet (GHS), which preserves these healing factors and facilitates their sustainable release until degradation of the sheet during the early healing of rotator cuff tear using a rat model.
Source: Journal of Shoulder and Elbow Surgery - Category: Orthopaedics Authors: Source Type: research