Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

This article exhibited a novel series of biphenyl-substituted diaryltriazines (BP-DATAs) as HIV-1 reverse transcriptase inhibitors targeting nonnucleoside binding pocket (NNIBP) to improve the positional adaptability.
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research