Ultramacrocyclization via selective catenation in water.

Ultramacrocyclization via selective catenation in water.
Chem Commun (Camb). 2019 Oct 15;:
Authors: Chen Q, Chen L, Wang CY, Jiao T, Pan Y, Li H
Abstract
A set of two cyclic [2]catenane dimers were self-assembled in aqueous media via selective hydrazone condensation, by means of either one-pot or post-functionalization procedures. Considering that each catenane is composed of two thirty-six member rings, each of these two cyclic [2]catenane dimers can be considered as a ultra-large macrocycle that contains more than fifty atoms in the ring framework. This cyclization methodology relying on catenation thus represents a novel approach for accomplishing ultramacrocyclization in pure water.
PMID: 31612173 [PubMed - as supplied by publisher]

Source: Chemical Communications - October 14, 2019 Category: Chemistry Authors: Chen Q, Chen L, Wang CY, Jiao T, Pan Y, Li H Tags: Chem Commun (Camb) Source Type: research