Histone H3F3/H3.3 chaperone DAXX converts to modulate SQSTM1 phase condensation for NFE2L2 activation.

This study suggests a new mechanism of SQSTM1 phase condensation by a protein-protein interaction, and indicates that cytoplasmic DAXX can play a role to regulate redox homeostasis.
PMID: 31607206 [PubMed - as supplied by publisher]

Source: Autophagy - October 13, 2019 Category: Cytology Authors: Yang Y, Valionyte E, Kelly J, Luo S Tags: Autophagy Source Type: research