Application of multivariate regression and artificial neural network modelling for prediction of physical and chemical properties of medicinal plants aqueous extracts

The objective of this study was to evaluate the applicability of multiple linear regression, nonlinear regression, piecewise linear regression, and artificial neural network modelling for the prediction of the physical properties (total dissolved solids, extraction yield), and chemical properties (total phenolic content and antioxidant activity) of the aqueous extracts of nine medicinal plants (dandelion, camomile, lavender, lemon balm, marigold, mint, nettle, plantain, and yarrow), prepared in dynamic experiments based on the extraction conditions (time and temperature), and plant species. Results indicated that simple multivariate regression models could be used for prediction of physical and chemical properties of medicinal plants aqueous extracts (the highest R2 were obtained for total phenolic content), while the artificial neural network proved a very effective tool (R2> 0.9) for simultaneous prediction of both physical and chemical properties of medicinal plants aqueous extracts.
Source: Journal of Applied Research on Medicinal and Aromatic Plants - Category: Complementary Medicine Source Type: research