Nodular Hiradenoma, a Rare Mimic of Breast Carcinoma Nodular Hiradenoma, a Rare Mimic of Breast Carcinoma

This case report summarizes the clinical, pathological, and immunohistochemical characteristics of a breast hidradenoma, an uncommon skin adnexal tumor arising from the eccrine or apocrine glands.Laboratory Medicine
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

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Authors: Macruz CF, Lima SMRR, Postigo S, Martins MM, Lucarelli AP, de Oliveira VM Abstract OBJECTIVE: To assess quality of life and climacteric symptoms for post-menopausal women receiving hormone therapy for breast cancer. METHODS: A prospective observational study of women treated at the Mastology Outpatient Clinic of the Department of Obstetrics and Gynecology was conducted between 2015 and 2019. Post-menopausal patients who had been diagnosed with breast cancer and who were experiencing climacteric symptoms were selected. These patients had undergone surgery, radiotherapy, and/or chemotherapy more than one...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
Conditions:   Anatomic Stage IV Breast Cancer AJCC v8;   Metastatic Breast Carcinoma;   Prognostic Stage IV Breast Cancer AJCC v8;   Recurrent Breast Carcinoma;   Refractory Breast Carcinoma Interventions:   Drug: Cyclophosphamide;   Biological: Allogeneic GM-CSF-secreting Breast Cancer Vaccine SV-BR-1-GM;   Biological: Pembrolizumab;   Biological: Recombinant Interferon Alpha 2b-like Protein;   Other: Questionnaire Administration;   Other: Quality of...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: In summary, these results indicate that the lncRNA LIFR-AS1 is a promising prognostic indicator in GC patients. PMID: 32495872 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
A new analysis shows that any diagnosis of ductal carcinoma in situ is associated with a long-term risk of invasive breast cancer and that treatment lowers this risk.Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Modern Pathology, Published online: 05 June 2020; doi:10.1038/s41379-020-0589-xInvasive apocrine carcinoma of the breast: clinicopathologic features and comprehensive genomic profiling of 18 pure triple-negative apocrine carcinomas
Source: Modern Pathology - Category: Pathology Authors: Source Type: research
Conditions:   Invasive Breast Cancer;   Breast-conserving Surgery Interventions:   Procedure: tumorectomy with axillary dissection (sentinel lymph node);   Radiation: per-operative partial irradiation Sponsor:   Institut du Cancer de Montpellier - Val d'Aurelle Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In conclusion, PTZ was hypothesized to act effectively on mitochondria of HepG2 cells; hence it should proceed into detailed drug targeting mechanism research. PMID: 32464002 [PubMed - indexed for MEDLINE]
Source: Journal of Environmental Pathology, Toxicology and Oncology - Category: Environmental Health Tags: J Environ Pathol Toxicol Oncol Source Type: research
Abstract Bioactivity-guided fractionation of the CHCl3-soluble extract of the roots of Paramignya trimera was carried out to obtain a new acridone alkaloid, paratrimerin I. Its structure was elucidated based on NMR spectroscopic data interpretation. Paratrimerin I showed noteworthy cytotoxicity against the HepG2 human hepatocellular and MCF-7 human breast carcinoma cell lines, with the submicromolar IC50 values of 0.43 and 0.26 µM, respectively. The N-methyl, C-4 methoxy, and C-5 hydroxy groups in the acridone skeleton can be proposed as a structural feature for good cytotoxicity. PMID: 32496136 ...
Source: Natural Product Research - Category: Biochemistry Authors: Tags: Nat Prod Res Source Type: research
AbstractBackgroundHistorically, more than one-third of patients with ductal carcinoma in situ (DCIS) treated with breast-conserving surgery (BCS) underwent additional surgery. The SSO-ASTRO guidelines advise 2  mm margins for patients with DCIS having BCS and whole-breast radiation (WBRT). Here we examine guideline impact on additional surgery and factors associated with re-excision.Patients and MethodsPatients treated with BCS for pure DCIS from August 2015 to January 2018 were identified. Guidelines were adopted on September 1, 2016, and all patients had separately submitted cavity-shave margins. Clinicopathologic c...
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
ConclusionsContrast-enhanced ultrasound features of IDCs have a certain correlation with pathological prognostic factors, which is conducive in assessing the prognosis of these patients.
Source: Japanese Journal of Radiology - Category: Radiology Source Type: research
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