Screening for diabetes in asymptomatic children: A simple and efficient method

ConclusionUrinalysis screening followed by evaluation of risk factors is a simple and efficient way to identify children with diabetes in schools.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research

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Authors: Janssen LGM, van Dam AD, Hanssen MJW, Kooijman S, Nahon KJ, Reinders H, Jazet IM, van Marken Lichtenbelt WD, Rensen PCN, Appelman-Dijkstra NM, Boon MR Abstract BACKGROUND: South Asians generally have an unfavourable metabolic phenotype compared with white Caucasians, including central obesity and insulin resistance. The Wnt protein family interacts with insulin signaling, and impaired Wnt signaling is associated with adiposity and type 2 diabetes mellitus. We aimed to investigate Wnt signaling in relation to insulin signaling in South Asians compared with white Caucasians. METHODS: Ten Dutch South Asia...
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Authors: Bae JH, Choi HJ, Cho KIK, Kim LK, Kwon JS, Cho YM Abstract BACKGROUND: To investigate the effects of a glucagon-like peptide-1 receptor agonist on functional brain activation in lean and obese individuals with type 2 diabetes mellitus (T2DM) in response to visual food cues. METHODS: In a randomized, single-blinded, crossover study, 15 lean and 14 obese individuals with T2DM were administered lixisenatide or normal saline subcutaneously with a 1-week washout period. We evaluated brain activation in response to pictures of high-calorie food, low-calorie food, and nonfood using functional magnetic resonan...
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
ConclusionFrom our current study, we conclude that even a very high maternal protein intake throughout lactation has no impact on growth and health parameters of the offspring.
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
CONCLUSION: It can be concluded that the presence of obesity may hinder the improvement of periodontal clinical parameters after conventional periodontal treatment in patients with diabetes mellitus and periodontitis. PMID: 31694983 [PubMed - in process]
Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
Authors: Tchang BG, Abel B, Zecca C, Saunders KH, Shukla AP Abstract Introduction: Obesity is a chronic disease caused by dysfunctional neurohormonal systems that result in excess weight, adiposopathy, and increased risk for many comorbidities including cardiovascular disease, type 2 diabetes, and certain types of cancer. Lorcaserin is a serotonergic agonist specific to the 5HT2C receptor that is FDA-approved for the long-term management of obesity in adults with BMI>30 kg/m2 or BMI>27 kg/m2 and at least one weight-related comorbidity.Areas covered: The authors review the pharmacodynamics and pharmacokinetic ...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
An investigational agent originally developed for sarcopenia has shown promise in a phase 2 trial in those with obesity and type 2 diabetes, leading to a loss of body fat as well as weight reduction.Medscape Medical News
Source: Medscape Pharmacist Headlines - Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news
There is evidence to suggest that frequent use of the sweeteners, especially in diet sodas, raises the risk of several chronic diseases, including obesity, metabolic syndrome, type 2 diabetes, and heart disease.
Source: WebMD Health - Category: Consumer Health News Source Type: news
TYPE 2 diabetes affects more than two million people in the UK, with being overweight a common risk factor. If it ’s left untreated, serious complications can occur, but adding a certain spice to your breakfast could prevent and control the condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
A Novel TNF-α Converting Enzyme (TACE) Selective Inhibitor JTP-96193 Prevents Insulin Resistance in KK-Ay Type 2 Diabetic Mice and Diabetic Peripheral Neuropathy in Type 1 Diabetic Mice. Biol Pharm Bull. 2019;42(11):1906-1912 Authors: Maekawa M, Tadaki H, Tomimoto D, Okuma C, Sano R, Ishii Y, Katsuda Y, Yoshiuchi H, Kakefuda R, Ohta T, Sasase T Abstract Tumor necrosis factor-α (TNF-α) converting enzyme/a disintegrin and metalloproteinase domain-containing protein 17 (TACE/ADAM17) is a key sheddase that releases TNF-α from its inactive precursor and is thought as a new drug targ...
Source: Biological and Pharmaceutical Bulletin - Category: Drugs & Pharmacology Authors: Tags: Biol Pharm Bull Source Type: research
Publication date: Available online 6 November 2019Source: JACC: Heart FailureAuthor(s): Milton PackerAbstractBoth obesity and type 2 diabetes are important risk factors for the development of heart failure with a preserved ejection fraction (HFpEF), and both disorders increase the risk of systemic thromboembolic events. Traditionally, the risk of stroke has been explained by the strong association of these disorders with atrial fibrillation (AF). However, adiposity and diabetes are risk factors for systemic thromboembolism, even in the absence of AF, because both can lead to the development of an inflammatory and fibrotic ...
Source: JACC: Heart Failure - Category: Cardiology Source Type: research
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