A lethal virus carried by ‘vampires’ is rampaging across the Americas

Nature, Published online: 08 October 2019; doi:10.1038/d41586-019-03005-5Viral genomes suggest that rabies strains carried by vampire bats travel from South America to North America, and vice versa.
Source: Nature AOP - Category: Research Source Type: research

Related Links:

AbstractDog demographics are considered as one of the main factors in the control of rabies. Having reliable data on dog population and husbandry practices on how they are managed is a key point in the elaboration of any control program to fight against human deaths due to rabies which are mainly due to dogs. However, the lack of data regarding dog population is one of the main hindrances to elaborate effective fighting projects in developing countries, particularly in Africa. In order to contribute for reliable data on dog demographics and husbandry practices related to rabies, this study was carried out in the cities of ...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
New research raises hopes of oral vaccine for dogs, the chief source of transmission to humansResearchers have discovered a way to stop rabies from shutting down critical responses in the immune system, a breakthrough that could pave the way for new tools to fight the deadly disease.Rabies kills almost60,000 people each year, mostly affecting poor and rural communities.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Global health Infectious diseases Global development Science Medical research Vaccines and immunisation World news Source Type: news
An estimated 60,000 people die of rabies each year, in part because of the lack of access to a cheap and simple vaccine – a new version could change that
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Condition:   Rabies Interventions:   Biological: ChAdOx2 RabG;   Biological: Inactivated Rabies Vaccine Sponsor:   University of Oxford Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
(PLOS) Every year, more than 59,000 people around the world die of rabies and there remains no cheap and easy vaccine regimen to prevent the disease in humans. Now, researchers report in PLOS Neglected Tropical Diseases that adding a specific immune molecule to a rabies vaccine can boost its efficacy.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
by Joseph R. Plummer, James P. McGettigan B cell activating factor (BAFF) is a member of the tumor necrosis factor (TNF) superfamily of cytokines that links innate with adaptive immunity. BAFF signals through receptors on B cells, making it an attractive molecule to potentiate vaccine-induced B cell responses. We hypothesized that a rabie s virus (RABV)-based vaccine displaying both antigen and BAFF on the surface of the same virus particle would target antigen-specific B cells for activation and improve RABV-specific antibody responses. To test this hypothesis, we constructed a recombinant RABV-based vector expressing vi...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
“In our ongoing commitment to address the supply shortages of rabies vaccine, we are making additional investments to increase production capacities to over 15 million doses annually,” added Krishna Ella, CMD, Bharat biotech International Ltd. The vaccine is presently manufactured at the WHO pre -qualified facility in Ankleshwar in Gujarat.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
“In our ongoing commitment to address the supply shortages of rabies vaccine, we are making additional investments to increase production capacities to over 15 million doses annually,” added Krishna Ella, CMD, Bharat biotech International Ltd. The vaccine is presently manufactured at the WHO pre -qualified facility in Ankleshwar in Gujarat.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
Publication date: Available online 12 November 2019Source: Preventive Veterinary MedicineAuthor(s): Felipe Rocha, Ricardo Augusto DiasAbstractThe importance of the common vampire bat Desmodus rotundus for the transmission of the rabies virus does not lie solely in its ability to transmit this disease to other mammals, but also in its capacity to adapt to environmental and climatic changes, granting them a wide geographical distribution. Control of this disease is currently based on culling of the vampire bat and vaccination of the livestock. A transmission model incorporating geographic and behavioral determinants of the v...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
(University of Melbourne) Researchers from Monash University and the University of Melbourne have found a way to stop the rabies virus shutting down the body's immune defence against it. In doing so they have solved a key scientific puzzle and have laid the foundation for the development of new anti-rabies vaccines.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
More News: Rabies | Research