Transplant group OKs change to lung policy

The organization that oversees national transplant policies has approved a one-year change that makes children younger than 12 eligible for priority on adult lung transplant lists, the group announced Monday.
Source: WDSU.com - Health - Category: Consumer Health News Source Type: news

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Authors: Liu C, Han M, Zhao L, Zhu M, Xu Q, Song Y, Wang H Abstract OBJECTIVE: This research aimed to explore the significance of low activity of ADAMTS-13 in acute myeloid leukemia (AML) after bone morrow transplantation (BMT), and to evaluate the disease progress and prognosis of the patients with low or normal activity of ADAMTS-13 after BMT. METHODS: 46 AML patients were included in our research. ADAMTS-13 activity was measured before BMT. Their medical indicators were recorded one month after BMT. All the patients were followed up and their disease progression was evaluated afterwards. The medical indicato...
Source: Hematology - Category: Hematology Tags: Hematology Source Type: research
Abstract PURPOSE: Post-operative pulmonary function is an important prognostic factor for lung transplantation. The purpose of this study was to identify factors affecting recovery of forced expiratory volume in 1 second (FEV1) at the first year after lung transplantation. MATERIALS AND METHODS: We retrospectively reviewed the medical records of lung transplantation patients between October 2012 and June 2016. Patients who survived for longer than one year and who underwent pulmonary function test at the first year of lung transplantation were enrolled. Patients were divided into two groups according to wheth...
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
ConclusionsLung and liver transplantation in AATD patients are associated with very good long-term survival rates that are comparable to, and sometimes superior to, other transplant indications. Although not currently recommended in AATD, LVRS may have a role in a minority of patients. The value of Alpha 1 Antitrypsin (AAT) augmentation therapy following lung transplantation requires further study. Wherever possible, AAT therapy should be continued in the period around elective surgeries.SummaryAlthough AATD is a widely discussed and researched topic in the literature, surgical intervention for AATD, in addition to the man...
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Recipient and donor age are well-known prognostic factors in adult heart transplantation. However, the association between donor and recipient age and their interaction and short- and long-term mortality is unknown.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
Alpha 1 Antitrypsin Deficiency (AATD) is a genetic cause of emphysema/chronic obstructive pulmonary disease (COPD) and liver disease, making AATD patients a high-risk surgical group. Additionally, patients may eventually require lung and/or liver transplantation or lung volume reduction surgery (LVRS). This narrative review discusses perioperative considerations for elective procedures in AATD patients, and reviews patient outcomes in AATD-related transplantation and LVRS.
Source: American Journal of Surgery - Category: Surgery Authors: Tags: Review Source Type: research
Until recently, lung transplantation was not considered in patients with human immunodeficiency virus (HIV). HIV seropositive patients with suppressed viral loads can now expect long-term survival with the adv...
Source: BMC Pulmonary Medicine - Category: Respiratory Medicine Authors: Tags: Case report Source Type: research
AbstractPatients with autoimmune disease –related interstitial lung disease (AID-ILD) occasionally develop radiologic pleuroparenchymal fibroelastosis (PPFE)–like lesions. However, the significance of AID as an etiology of PPFE has not been fully elucidated. The aim of this study is to verify the increase of elastic fibers in AID-ILD p atients and evaluate the prevalence of histological PPFE in patients with AID-ILD. We selected cases of clinically diagnosed AID-ILD and idiopathic pulmonary fibrosis (IPF), in which an autopsy had been performed or in which the patient had undergone pneumonectomy for lung transp...
Source: Virchows Archiv - Category: Pathology Source Type: research
AbstractThe overall aim of this scoping review of the literature is twofold: (1) to provide an overview of all instruments that have been used to assess health-related quality of life (HRQoL) after solid organ transplantation and (2) to provide a list of health items they include to support future studies on the development of a new-generation HRQoL instrument. All studies that administered any form of HRQoL instrument to post-transplant solid organ recipients were identified in a comprehensive search of PubMed (MEDLINE), Embase, and Web of Science, with a cut-off date of May 2018. The search used various combinations of t...
Source: The Patient - Patient-Centered Outcomes Research - Category: International Medicine & Public Health Source Type: research
A 62-year old non-smoker, Caucasian male was evaluated for lung transplantation based on severe upper-lobe predominant emphysema with superimposed fibrosis in the lower lung zones (Figure 1). The patient had no significant exposure history, and prior work-up for alpha-1-antitrypsin deficiency, autoimmune disease, and hypersensitivity pneumonitis was unremarkable. The diagnosis of Niemann Pick disease, type B was eventually established based on a compatible family history with an almost identical disease presentation in a sibling.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Case Anecdotes, Comments and Opinions Source Type: research
Infections of the driveline exit site are very common and are one of the most common reasons for readmissions of patients with left ventricular assist devices (LVAD). The risk for LVAD infection increases with the duration of LVAD support and after 48 months it is among the top three reasons for death [1-3]. The rate of mortality from LVAD-related mediastinitis is as high as 70% [4,5].
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Case Anecdotes, Comments and Opinions Source Type: research
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