Committee allows special review for children's lung transplants
But the national organization rejected making an emergency rule to allow kids to qualify for adult lungs
This study aims to examine outcomes of patients who received ECMO as a bridge to lung transplantation.MethodsStatistical analysis was performed on data gathered retrospectively from the electronic medical records of adult patients who received ECMO as BTT at Columbia University Medical Center from April 2009 through July 2018.ResultsOne hundred and twenty-one adult patients were placed on ECMO as bridge to lung transplantation. Seventy (59%) patients were successfully bridged to lung transplantation. Simplified Acute Physiology Score II, unplanned endotracheal intubation, renal replacement therapy, and cerebrovascular acci...
Primary graft dysfunction (PGD) is the most important contributor to early morbidity and mortality in lung transplant recipients and reflects a combination of allograft ischemia-reperfusion injury, vasogenic pulmonary edema and inflammatory changes mediated by the innate immune system.1,2,3 Patients who develop PGD are at increased risk of poor lung function and death.4-6 There are limited therapeutic options available to patients who develop PGD after lung transplantation and as such, the main focus has been on the identification of risk factors for PGD and prevention strategies.
Mechanical circulatory support devices, i.e., Left Ventricular Assist Devices (LVADs), are increasingly utilized for hemodynamic restoration in patients with advanced and end-stage heart failure.1 The latest generation of miniaturized, continuous-flow LVADs has afforded enhanced patient survival and quality of life compared to earlier pulsatile pneumatic systems, and is now approved for both bridge-to-transplant as well as for definitive destination therapy.1 Despite clinical efficacy of these devices, LVAD thrombosis, either in the form of pump thrombosis or as thromboembolic events, remains a common and vexing complicati...
Publication date: Available online 16 February 2019Source: Social Science &MedicineAuthor(s): Athena EngmanAbstractThe concept of biographical disruption has now enjoyed nearly 40 years of use in medical sociology. This paper argues that taking an embodied approach to biographical disruption helps to explain the concept's enduring efficacy. Drawing on the work of Maurice Merleau-Ponty and contemporary theories of embodiment inspired by his phenomenology, this paper advances that biographical disruption involves, in the first instance, a disruption to the ability to enact an embodied orientation towards the world. Biogr...
In this report, early graft dysfunction was diagnosed at day 3 and the patient was empirically treated with antibiotics and high dose corticosteroid therapy. Death occurred on the 29th post-operative day and an autopsy revealed abundance of foamy macrophages in lung tissue consistent with ASMD cells.
Professor Francis Fontan, the pioneer in the field of congenital heart surgery and former president of the European Association for Cardio-Thoracic Surgery, recently passed away in January 2018. The ‘Fontan operation’,1 the final stage in a series of cardiac repairs for children with single ventricle anatomy, saved the lives of numerous children and is undoubtedly one of the greatest milestones in surgical history. However, Professor Fontan himself was among the first to notice the palliati ve nature of the Fontan circulation.
Tiffany Senter (pictured) of Shasta Lake City, California is only 25, but she's been at deaths door twice. Tiffany was born with cystic fibrosis and has had to have two lung transplants.