Class(y) dissection of BRAF heterogeneity: beyond non-V600.

Class(y) dissection of BRAF heterogeneity: beyond non-V600.
Clin Cancer Res. 2019 Oct 04;:
Authors: Fontana E, Valeri N
Abstract
Different classes of BRAF mutations are present in colorectal and other cancers. Non-V600 mutations are rare; however, their detection rate will increase as the use of next-generation sequencing ramps up quickly in clinical practice. Different biochemical signalling pathways are active in non-V600 BRAF mutant cancers and may affect treatment response.
PMID: 31585936 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - October 3, 2019 Category: Cancer & Oncology Authors: Fontana E, Valeri N Tags: Clin Cancer Res Source Type: research