Progress Toward Poliovirus Containment Implementation - Worldwide, 2018-2019.

Progress Toward Poliovirus Containment Implementation - Worldwide, 2018-2019. MMWR Morb Mortal Wkly Rep. 2019 Sep 27;68(38):825-829 Authors: Moffett DB, Llewellyn A, Singh H, Saxentoff E, Partridge J, Iakovenko M, Roesel S, Asghar H, Baig N, Grabovac V, Gurung S, Gumede-Moeletsi N, Barnor J, Theo A, Rey-Benito G, Villalobos A, Boualam L, Swan J, Sutter RW, Pandel E, Wassilak S, Oberste MS, Lewis I, Zaffran M, MEng Abstract Among the three wild poliovirus (WPV) types, type 2 (WPV2) was declared eradicated globally by the Global Commission for the Certification of Poliomyelitis Eradication (GCC) in 2015. Subsequently, in 2016, a global withdrawal of Sabin type 2 oral poliovirus vaccine (OPV2) from routine use, through a synchronized switch from the trivalent formulation of oral poliovirus vaccine (tOPV, containing vaccine virus types 1, 2, and 3) to the bivalent form (bOPV, containing types 1 and 3), was implemented. WPV type 3 (WPV3), last detected in 2012 (1), will possibly be declared eradicated in late 2019.* To ensure that polioviruses are not reintroduced to the human population after eradication, World Health Organization (WHO) Member States committed in 2015 to containing all polioviruses in poliovirus-essential facilities (PEFs) that are certified to meet stringent containment criteria; implementation of containment activities began that year for facilities retaining type 2 polioviruses (PV2), including type 2 oral poliovirus vaccine (OPV) materia...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research

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[This Day] To further demonstrate commitment of Canadian government to the fight against polio virus and strengthen routine immunisation (RI), the Director General West and Central African Bureau, Global Affairs Canada, Mr Tarik Khan, joined the Niger State Primary Healthcare Development Agency (SPHCDA) and WHO staff during the polio house-to-house vaccination exercise recently.
Source: AllAfrica News: Polio - Category: Infectious Diseases Source Type: news
Polio cases around have declined globally by more than 99 percent since 1988, but the type 1 poliovirus remains endemic in Pakistan and Afghanistan, where it has made a comeback this year and infected 102 people. Credit: Ashfaq Yusufzai/IPS By James ReinlUNITED NATIONS, Nov 20 2019 (IPS) Efforts to wipe polio off the face of the planet took a step forward this week, with a multibillion-dollar fundraiser in the Middle East helping eradication schemes tackle a virus that disproportionately kills and cripples children in poor countries. Donor governments and philanthropists pledged $2.6 billion on Tuesday in Abu Dhabi to...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Aid Asia-Pacific Development & Aid Featured Global Headlines Health IPS UN: Inside the Glasshouse Poverty & SDGs Regional Categories TerraViva United Nations polio eradication World Health Organization (WHO) Source Type: news
In this report, we described a child with acute flaccid paralysis may be caused by poliovirus vaccine. To provide the feasible ways to realize or reduce the risk of neurological adverse events caused by vaccines, we further provide a mini review of literatures of vaccination associated neurological adverse events. This revealed that oral poliomyelitis vaccine use exclusively and type 2 serotype poliomyelitis vaccine virus were the risk factor of VAPP. Combination vaccine was associated with an increased risk of ADEM and FS following immunization, when compared with administration of vaccines separately. Even though cases h...
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
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Source: AllAfrica News: Polio - Category: Infectious Diseases Source Type: news
This report updates previous reports on Pakistan's polio eradication activities, progress, and challenges (2,3). In 2018, Pakistan reported 12 WPV1 cases, a 50% increase from eight cases in 2017, and a 31% increase in the proportion of WPV1-positive sites under environmental surveillance (i.e., sampling of sewage to detect poliovirus). As of November 7, 2019, 80 WPV1 cases had been reported, compared with eight cases by the same time in 2018. An intensive schedule of supplementary immunization activities (SIAs)* implemented by community health workers in the core reservoirs (i.e., Karachi, Peshawar, and Quetta) where WPV1 ...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
This report presents data on cVDPV outbreaks detected during January 2018-June 2019 (as of September 30, 2019). Compared with January 2017-June 2018 (3), the number of reported cVDPV outbreaks more than tripled, from nine to 29; 25 (86%) of the outbreaks were caused by cVDPV2. The increase in the number of outbreaks in 2019 resulted from VDPV2 both inside and outside of mOPV2 response areas. GPEI is planning future use of a novel type 2 OPV, stabilized to decrease the likelihood of reversion to neurovirulence. However, all countries must maintain high population immunity to decrease the risk for cVDPV emergence. Cessation ...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Abstract Hexavalent vaccines containing diphtheria, tetanus, pertussis, Haemophilus influenzae type b, poliomyelitis, and hepatitis B virus antigens have the potential to be used for the primary series in India (6, 10, 14 weeks of age) and the toddler booster dose. Three hexavalent vaccines are available in India: DTwP-Hib/HepB-IPV (wP-hexa), DTaP-IPV-HB-PRP~T(2aP-hexa), and DTaP-HBV-IPV/Hib (3aP-hexa). In the three published phase-3 Indian studies, pertussis 'vaccine response' rates 1 month after a 6-10-14-week primary series were 68.4-75.7% for wP-hexa, 93.8-99.3% for 2aP-hexa, and 97.0-100% for 3aP-hexa; seropr...
Source: Indian Pediatrics - Category: Pediatrics Authors: Tags: Indian Pediatr Source Type: research
Afghanistan and Pakistan are the only countries that continue to confirm ongoing wild poliovirus type 1 transmission.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Polio (poliomyelitis) Polio Vaccination Population health Source Type: news
Since the launch of the Global Polio Eradication Initiative in 1988 and broad use of live, attenuated oral poliovirus vaccine, the number of wild poliovirus cases has declined>99.99%.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Diabetes Eye and Vision Health MMWR Morbidity & Mortality Weekly Report Outbreaks Polio (poliomyelitis) Polio Vaccination Population health Smoking Tobacco Use Vaccines Cigarette Smoking Source Type: news
A Nigerian father who used to chase health workers away from his home has a change of heart.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
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